1 | Author | Wilhelm Hasselbach, A. Ndrea Migala, Gafni, P. D. Boyer | Requires cookie* |
Title | Invariance of Stoichiometry of the Sarcoplasmic Reticulum Calcium Pump at Physiological Calcium Concentrations — a Reevaluation ![]() | ||
Abstract | The decline of the transport ratio of the sarcoplasmic calcium pump observed in a recent study (A. results from the retardation of calcium oxalate precipitation at low calcium/protein ratios. The prevailing high internal calcium level supports a rapid calcium backflux and a compensatory ATP hydrolysis during net calcium uptake which reduces the transport ratio. Yet, the determined calcium back flux does not fully account for the decline of the transport ratio. A supposed modulation of the stoichiometry of the pump by external calcium (0.1 ^m) is at variance with results of previous studies showing a constant transport ratio of two in the same calcium concentration range. | ||
Reference | Z. Naturforsch. 40c, 571—575 (1985); received May 20 1985 | ||
Published | 1985 | ||
Keywords | Sarcoplasmic Reticulum, Calcium Pump, Stoichiometry | ||
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