Go toArchive
Browse byFacets
Bookbag ( 0 )
'Tumor Cells' in keywords Facet   Publication Year 1980  [X]
Results  1 Item
Sorted by   
Section
Publication Year
1980[X]
1Author    Ping-Lu LiRequires cookie*
 Title    Cytotoxicity of Cobra (Naja naja kaouthia) Venom on Rabbit Red Blood Cells and S-180 Tumor Cells in the Presence of Tetracaine, Lidocaine and Procaine  
 Abstract    The cytocidal action of Naja naja kaouthia venom on rabbit red blood cells and S-180 tumor cells treated with local anesthetics (tetracaine, lidocaine and procaine) were studied. The S-180 cells were more sensitive to the venom than the red blood cells which required albumin for ef­ ficient hemolysis in the 10 minute assay. All three local anesthetics at lower concentrations protected both cell types against venom hemolysis. At higher concentrations the local anesthetics enhanced the cell lysis to 100%. The effectiveness of the local anesthetics for both the inhibition and enhancement phases of cytotoxicity was tetracaine > lidocaine > procaine. This is the same order as their anesthetic effectiveness, lipid solubility and their protein binding. 
  Reference    Z. Naturforsch. 35c, 268 (1980); received October 8 1979 
  Published    1980 
  Keywords    Local Anesthetics, Cobra Venom, Cytotoxicity, Erythrocytes, Tumor Cells 
  Similar Items    Find
 DEBUG INFO      
 TEI-XML for    default:Reihe_C/35/ZNC-1980-35c-0268.pdf 
 Identifier    ZNC-1980-35c-0268 
 Volume    35