| | 1 | Author
| NigelC P Baldwin, BarrieW. Bycroft, PaulM. Dewick, John Gilbert, Ian Holden | Requires cookie* | | | Title
| Biosynthesis of Trichothecene My cotoxins in Fusarium culmorum Cultures  | | | | Abstract
| A high yielding production of the trichothecene mycotoxin 3-acetyldeoxynivalenol (3-AcDON) in cultures of Fusarium culmorum is described. By supplying [14C]acetate, 14C-labelled 3-AcDON suitable for further metabolic studies has been obtained. The pattern of labelling has been ascertained by using 13C-labelled acetate precursors, and is in line with established biosynthetic data. A second trichothecene produced in significant amounts by F. culmorum has been identified as 3a, 15-diacetoxy-7a, 8a-dihydroxy-12, 13-epoxytrichothec-9-ene (7a, 8 a-dihydroxycalonec-trin). | | | |
Reference
| Z. Naturforsch. 40c, 514—518 (1985); received May 8 1985 | | | |
Published
| 1985 | | | |
Keywords
| Mycotoxin, Trichothecene, Fusarium, Biosynthesis, 3-Acetyldeoxynivalenol | | | |
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| | | | | TEI-XML for
| default:Reihe_C/40/ZNC-1985-40c-0514.pdf | | | | Identifier
| ZNC-1985-40c-0514 | | | | Volume
| 40 | |
| 2 | Author
| NigelC P Baldwin, BarneW. Bycroft, PaulM. Dewick, John Gilbert | Requires cookie* | | | Title
| Metabolie Conversions of Trichothecene Mycotoxins: Biotransformation of 3-AcetyldeoxynivaIenoI into Fusarenon-X | | | | Abstract
| The trichothecene mycotoxin 3-acetyldeoxynivalenol was transformed by cultures of the diace-toxyscirpenol producer Fusarium sp. strain C37410-90 into four compounds, identified as deoxy-nivalenol, 15-acetyldeoxynivalenol, 3,15-diacetyldeoxynivalenol and fusarenon-X. The major transformations are the result of specific esterification and de-esterification processes, but the production of fusarenon-X involves in addition a novel 4ß-hydroxylation of the trichothecene ring system itself. | | | |
Reference
| Z. Naturforsch. 41c, 845 (1986); received April 21 1986 | | | |
Published
| 1986 | | | |
Keywords
| Mycotoxin, Trichothecene, Fusarium, Biotransformation, 3-Acetyldeoxynivalenol | | | |
Similar Items
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| | | | | TEI-XML for
| default:Reihe_C/41/ZNC-1986-41c-0845.pdf | | | | Identifier
| ZNC-1986-41c-0845 | | | | Volume
| 41 | |
|
