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1990 (1)
1980 (1)
1Author    Qamar Khalid, M.Ataur RahmanRequires cookie*
 Title    Studies on Synergism between Glucose and Amino Acids with Respect to Insulin Release in vitro  
 Abstract    The mutual enhancement of the effect of insulin release by glucose and amino acids is not clearly understood. Present in vitro studies with isolated rat islets were undertaken to elaborate the role of amino acids on insulin release, particularly their interaction with glucose as well as among each other, which has been reported to lead to synergism in the hum an subjects. In the presence of 8.3 mM glucose, both arginine, as well as, leucine potentiated the effect of glucose which increased progressively with the increasing concentrations of the amino acid. This effect of arginine was not synergistic in nature because arginine did not stimulate insulin release in the absence of glucose. The effect of glucose and leucine was found to be additive and not synergistic. No synergism was exhibited by any o f the am ino acid pairs tested in the present study. Thus both phenylalanine and lysine did not potentiate the effect o f either arginine or leucine. Arginine showed a mild, but significant potentiating effect on leucine-stimulated insulin release. It is suggested that synergism between glucose and amino acids and between certain am ino acid pairs reported in m an may not be due to the direct effects of these stimuli on the beta cells, but some other factors in vivo may be involved. 
  Reference    Z. Naturforsch. 35c, 72—7 (1980); received September 3 1979 
  Published    1980 
  Keywords    Insulin Release, Glucose, Amino Acids, Synergism, Rat Islets 
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 TEI-XML for    default:Reihe_C/35/ZNC-1980-35c-0072.pdf 
 Identifier    ZNC-1980-35c-0072 
 Volume    35 
2Author    Carl Fedtke, RobertH. Strang, Bayer Ag, Geschäftsbereich Pflanzenschutz, Biologische Anwendungstechnik, ForschungRequires cookie*
 Title    Synergistic Activity of the Herbicide Safener Dichlormid with Herbicides Affecting Photosynthesis  
 Abstract    Dichlormid, a safener for thiolcarbamate herbicides, was tank-mixed with several herbicidal inhibitors of photosystem II, or with the herbicide acifluorfen, and applied postemergence to Ipomoea hederacea plants. Dichlormid had no visible effects on the plants when applied alone, but interacted synergistically with the herbicides in the combination treatments. Dichlormid strongly decreased the ascorbic acid levels in the Ipom oea hederacea cotyledons. Ascorbate is known to protect plant tissue from photooxidative damage. The herbicides which interacted synergistically with dichlormid are believed to generate their phytotoxic action via the produc­ tion of excess singlet oxygen. It is suggested that the decreased ascorbate levels in the Ipomoea hederacea cotyledons after dichlormid treatment result in an impaired singlet oxygen scaveng­ ing system and consequently lead to increased plant damage in the presence of singlet oxygen generating herbicides. 
  Reference    Z. Naturforsch. 45c, 565—567 (1990); received October 13 1989 
  Published    1990 
  Keywords    Herbicide, Synergism, Safener, Oxygen Toxicity, Ascorbic Acid 
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 TEI-XML for    default:Reihe_C/45/ZNC-1990-45c-0565.pdf 
 Identifier    ZNC-1990-45c-0565 
 Volume    45