| 1 | Author
| O. Rlando, M. Uñoz3, RaúlC. Peñab, Enrique Ureta, GloriaM. Ontenegro0, B. Arbara, N. Timmermannc | Requires cookie* | | Title
| Propolis from Chilean Matorral Hives  | | | Abstract
| Viscidone (0.5%), vanillin, 3',4'-(m ethylendioxy)acetophenone, 3-ethoxy-4-methoxybenz-aldehyde, cinnamic acid, 3-methoxy-4-hydroxymethyl ester were isolated from propolis o f hives from Cuncumen. This is the first report on propolis composition o f an arid and a Mediterranean type climate area. | | |
Reference
| Z. Naturforsch. 56c, 269 (2001); received September 8/N ovem ber 16 2000 | | |
Published
| 2001 | | |
Keywords
| Propolis, Structure Elucidation, Plant Sources | | |
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| default:Reihe_C/56/ZNC-2001-56c-0269.pdf | | | Identifier
| ZNC-2001-56c-0269 | | | Volume
| 56 | |
3 | Author
| H. Lert, K. T. Araz, H. Budzikiewicz | Requires cookie* | | Title
| Serratiochelin, a New Catecholate Siderophore from Serratia marcescens  | | | Abstract
| The catecholate siderophore serratiochelin isolated from an iron deficient culture medium of Serratia marcescens TW was characterized by mass spectrometry and NMR and by GC/MS analysis of the hydrolysis products as l-(2,3-dihydroxybenzamido)-3-[4 S,5i?-2-(2,3-dihy-droxyphenyl)-5-methyl-2-oxazoline-4-carboxamido]propane. The structure of serratiochelin was confirmed by synthesis. The bacterial strain also produces chrysobactin. In tro d u ctio n | | |
Reference
| Z. Naturforsch. 49c, 11—17 (1994); received October ll/D ecem ber 201993 | | |
Published
| 1994 | | |
Keywords
| Catecholate Siderophore, Serratiochelin, Chrysobactin, Structure Elucidation, Serratia marcescens | | |
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| default:Reihe_C/49/ZNC-1994-49c-0011.pdf | | | Identifier
| ZNC-1994-49c-0011 | | | Volume
| 49 | |
4 | Author
| Michael Assmann3, VictorW. Rayb, RobW M Van Soestc, Peter Proksch3 | Requires cookie* | | Title
| Aiolochroia crassa*  | | | Abstract
| A detailed analysis of the chemical constituents of a Caribbean specimen of Aiolochroia crassa was performed. Five brominated products (1 -5) were isolated and one of these was a new bromotyrosine metabolite. The structure of the new compound 1 has been established from spectral studies. Compounds 1 and 2, which are the major brominated metabolites and have not been previously identified in any Aiolochroia species, could be usefully employed as chemotaxonomic markers. | | |
Reference
| Z. Naturforsch. 53c, 398 (1998); received April 8 1998 | | |
Published
| 1998 | | |
Keywords
| Sponges, Aiolochroia crassa, Isoxazoline Alkaloids, Structure Elucidation | | |
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| default:Reihe_C/53/ZNC-1998-53c-0398.pdf | | | Identifier
| ZNC-1998-53c-0398 | | | Volume
| 53 | |
5 | Author
| Ru Angelie, Edrada3, Victor Wrayb, Ludger Wittec, Leen Van Ofwegend, Peter Proksch3 | Requires cookie* | | Title
| Bioactive Terpenes from the Soft Coral Heteroxenia sp. from Mindoro, Philippines  | | | Abstract
| 0 0 4 9 /9 31-8886182. E-m ail: proksch@botanik.uni-wuerzburg.de b Gesellschaft für Biotechnologische Forschung mbH, M ascheroder Weg A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philip pines yielded two cadinene sesquiterpenes, (+)-a-m uurolene (1) and a novel derivative (+)-6 -hydroxy-a-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldost-erol A (3). The structure of the novel compound was unambiguously established on the basis of NM R spectroscopic (! H, 13C, CO SY, ! H-detected direct and long range 13C -'H correla tions) and mass spectrom etric (E IM S) data. All compounds were active against the phytopa-thogenic fungus Cladosporium cucum erinum . The isolated terpenes were also active in the brine shrimp lethality test. | | |
Reference
| Z. Naturforsch. 55c, 82—8 (2000); received August 1999 | | |
Published
| 2000 | | |
Keywords
| Corals, Heteroxenia, Cadinene Sesquiterpenes, Structure Elucidation, Bioactivity | | |
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| default:Reihe_C/55/ZNC-2000-55c-0082.pdf | | | Identifier
| ZNC-2000-55c-0082 | | | Volume
| 55 | |
7 | Author
| R. Teeyapant3, H.J W Oerdenbagb, P. Kreis3, J. Hacker0, V. W. Rayd, L. Witte6, P. Proksch3 | Requires cookie* | | Title
| Antibiotic and Cytotoxic Activity of Brominated Compounds from the Marine Sponge Verongia aerophoba  | | | Abstract
| Analysis of the marine sponge Verongia aerophoba from the Canary Islands afforded eight brominated secondary metabolites including the small molecular weight compounds aeroply-sinin-1 (5) and the dienone (7) which were previously shown to arise by enzymatically cata lyzed degradation of aerophobin-2 (4) and isofistularin-3 (1) following breakdown of the cellu lar compartmentation o f the sponge. All compounds were identified from their NM R and mass spectra. Aeroplysinin-1 as well as dienone which arise from isofistularin-3 or aeropho bin-2 by biotransformation within the sponge showed a significantly higher antibiotic as well as cytotoxic activity than their biogenetic precursors. Antibiotic activity was studied with re spect to several gram-positive and gram-negative bacteria including B. subtilis, S. aureus and E. coli. The MICs (MBCs) of aeroplysinin-1 (5) and the dienone (7) varied between 12.5-25 (50-100) ng/ml respectively. Cytotoxicity was tested in vitro towards HeLa cells, a human cervix uteri tumour cell line. Aeroplysinin-1 (5) and the dienone (7) displayed pronounced cytotoxic activity with IC50s of 3.0 and 3.2 |iM respectively. A five-fold increase in cytotoxicity was observed after O-acetylation of the dienone (7). The IC50 of the dienone O-acetate (0.6 ^im) was comparable to that o f the clinically used anticancer drug cisplatin (0.7 ^m). | | |
Reference
| Z. Naturforsch. 48c, 939—945 (1993); received July 16/August30 1993 | | |
Published
| 1993 | | |
Keywords
| Verongia aerophoba, Sponges, Secondary Metabolites, Structure Elucidation, Antibiotic Activity | | |
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| default:Reihe_C/48/ZNC-1993-48c-0939.pdf | | | Identifier
| ZNC-1993-48c-0939 | | | Volume
| 48 | |
10 | Author
| SiegmUnd Lang, H.Anna Beyer, P. Eter, Sistig, F. Ritz, W. Ag, N. Er | Requires cookie* | | Title
| A New Red Dipyrromethene Pigment from Candida boidinii  | | | Abstract
| The yeast Candida boidinii ATCC 32195 produces a cell-bound red pigment during growth on 1% ethanol in the presence o f 0.05% monofluoracetate. Its isolation and purification are described. The structure was elucidated by chemical degradation and physical m ethods, m ainly mass and nuclear magnetic resonance spectroscopy. | | |
Reference
| Z. Naturforsch. 38c, 7 (1983); received September 15/O ctober 28 1982 | | |
Published
| 1983 | | |
Keywords
| Candida boidinii, Growth on Ethanol, Presence M onofluoracetate, Red Dipyrrom ethene Pigment, Structure Elucidation | | |
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| default:Reihe_C/38/ZNC-1983-38c-0007.pdf | | | Identifier
| ZNC-1983-38c-0007 | | | Volume
| 38 | |
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