| 2 | Author
| Akira Taketo, Yoriko Taketo | Requires cookie* | | Title
| Effects of Membrane-Acting Drugs and Aerobiosis on Production of Streptolysin S and Nuclease in Hemolytic Streptococci  | | | Abstract
| Yield of streptolysin S (SLS) in streptococcal culture was considerably reduced by procaine, dibucaine, atropine or chlorpromazine at concentrations which scarecely affected production of an extracellular nuclease as well as the bacterial growth. Cerulenin was also inhibitory to SLS formation, but its effect was more pronounced on the nuclease production. By aerobiosis, amount of SLS produced into culture supernatant was increased significantly, whereas yield of the nuclease was rather unaffected. | | |
Reference
| Z. Naturforsch. 39c, 1128—1131 (1984); received August 14 1984 | | |
Published
| 1984 | | |
Keywords
| Streptolysin S, Nuclease, Membrane, Aerobiosis, Streptococci | | |
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| default:Reihe_C/39/ZNC-1984-39c-1128.pdf | | | Identifier
| ZNC-1984-39c-1128 | | | Volume
| 39 | |
3 | Author
| Akira Taketo, Yoriko Taketo | Requires cookie* | | Title
| Enhanced Production of Cell-Bound and Extracellular Streptolysin S by Hemolytic Streptococci Pretreated with Proteases  | | | Abstract
| The amount o f streptolysin S produced by resting streptococci was considerably increased after incubation o f the washed bacteria with trypsin or pronase. Production o f both cell-bound and free forms o f the toxin was enhanced by the protease treatment. By addition o f trypsin, streptolysin S yield was considerably increased in growing culture as well. Treatment with lysozyme was ineffective, and the toxin production was only slightly prom oted by preincubation with hyaluronidase or Chymotrypsin. In contrast, pretreatment with chymotrypsin caused in creased production o f an extracellular nuclease, whereas the yield o f this enzyme was reduced after incubation o f the cocci with pronase. Evidence was obtained indicating de novo synthesis o f the exotoxin in the protease-treated bacteria. | | |
Reference
| Z. Naturforsch. 40c, 166 (1985); received N ovem ber 22 1984 | | |
Published
| 1985 | | |
Keywords
| Streptolysin S, Cell-Bound Hemolysin, Protease, Streptococci | | |
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| default:Reihe_C/40/ZNC-1985-40c-0166.pdf | | | Identifier
| ZNC-1985-40c-0166 | | | Volume
| 40 | |
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