| 1 | Author
| Georg Rampold, Elsa Lundanes, Karl Folkers, Wolfgang Voelter, Hubert Kalbacher+, Emile Bliznakov | Requires cookie* | | Title
| Solid Phase Synthesis of Thymopoietin-(32-36) Using Adpoc Amino Acids and its Biological Activity +  | | | Abstract
| An exemplary peptide has been synthesized for the first time by an automated solid-phase instrumentation which utilized the new Adpoc (1 -(1-adamantyl) -1 -methylethoxycarbonyl-) group for protection of the a-amino groups of the amino acids. The pentapeptide, thymo-poietin-(32-36) was synthesized, and shown to be pure by criteria including HPLC. Using a Cytoxan (cyclophosphamide) model system for suppression of a primary, hemolytic, humoral, antibody level, thymopoietin-(32-36) showed low activity, and reversed the suppressing effect of Cytoxan. This biological activity apparently is the result of cum-mulative effect. | | |
Reference
| Z. Naturforsch. 35b, 1476—1478 (1980); received May 27 1980 | | |
Published
| 1980 | | |
Keywords
| Adpoc Amino Acids, Solid Phase Synthesis, Thymopoietin-(32-36) | | |
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| default:Reihe_B/35/ZNB-1980-35b-1476.pdf | | | Identifier
| ZNB-1980-35b-1476 | | | Volume
| 35 | |
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