| | 1 | Author
| Reinhold Tacke, Haryanto Linoh, MoayadT. Attar-Bashi, WilliamS. Sheldrick, Ludger Ernst, Roland Niedner, Joachim Frohnecke | Requires cookie* | | | Title
| Sila-Pharmaka, 26. Mitt. [1] Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, III Sila-Pharmaca, 26th Communication [1] Preparation and Properties of Silicon Compounds with Potential Curare-Like Activity, III  | | | | Abstract
| The potentially curare-hke silicon compounds 8a-Sf were synthesized and investigated with respect to their structure-activity relationships. The conformations of the com-pounds in the solid state and in solution were studied by X-ray diffraction analysis (8a-8e) and *H NMR spectroscopy (8a-8f), respectively. The muscle relaxing properties of 8a-8f were investigated on the mouse. The observed structure-activity relationships are not in accordance with the classical "14 A model" for neuromuscular blocking agents. Einführung | | | |
Reference
| Z. Naturforsch. 37b, 1461—1471 (1982); eingegangen am 19. April 1982 | | | |
Published
| 1982 | | | |
Keywords
| Silicon Compounds, Curare-Like Activity, X-ray, Conformational Analyses, Structure-Activity Relationships | | | |
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| default:Reihe_B/37/ZNB-1982-37b-1461.pdf | | | | Identifier
| ZNB-1982-37b-1461 | | | | Volume
| 37 | |
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