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'Sesquiterpenoids' in keywords Facet   Publication Year 1995  [X]
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1995[X]
1Author    Z. NaturforschRequires cookie*
 Title    Kuehneromycins A and B, Two New Biological Active Compounds from a Tasmanian Kuehneromyces sp. (Strophariaceae, Basidiomycetes)  
 Abstract    G erh ard E rk e l3, K irsten L o ren zen 3, Timm A n k ea, R obert V eltenb, A lb erto G im en ezb, and W olfgang Steglichb In a search for new inhibitors of RNA-directed DNA-polymerases kuehneromycin A (1) was isolated from fermentations of a Tasmanian Kuehneromyces species. Its structure was elucidated by spectroscopic methods. Kuehneromycin A (1) is a non-competitive inhibitor of avian myeloblastosis virus (Kj 200 ^i m) and moloney murine leukemia virus (K; 40 (.i m) reverse transcriptases. The second compound, kuehneromycin B (2) is a strong inhibitor of platelet aggregation stimulated with different inducers. In addition, both compounds exhibit cytotoxic and antimicrobial activities. 
  Reference    Z. Naturforsch. 50c, 1 (1995); received October 5 1994 
  Published    1995 
  Keywords    Kuehneromyces sp, Basidiomycetes, Sesquiterpenoids, Drimanes, Nordrimanes 
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 TEI-XML for    default:Reihe_C/50/ZNC-1995-50c-0001.pdf 
 Identifier    ZNC-1995-50c-0001 
 Volume    50