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1990 (1)
1Author    U. HoegerRequires cookie*
 Title    Fate of Circulating Serotonin in the Hemolymph of the Crayfish, Orconectes limosus  
 Abstract    The fate of injected [14C]serotonin (0.1 nCi/1.6nmol per animal) was investigated in the crayfish Orconectes limosus after injection. Specific radioactivities reached highest values in the green gland, followed by intestine, gills, nervous tissue and digestive gland. Label accumu­ lation was lowest in the tail muscle. Cold serotonin injected into the hemolymph (50 nmol/100 g wet wt) was cleared with a mean half life of 12.9 +/— 2.6 min (15 °C; N = 5). By HPLC separation of hemolymph samples taken at intervals after the injection of [l4C]serotonin, the formation of a metabolic product could be demonstrated. The formation of the metabolite was not, however, detectable by na­ tive fluorescence, suggesting the metabolic breakdown of the indole ring. The combined amounts of acid soluble radioactivity recovered from hemolymph, green gland, digestive gland and intestine yielded 80-100%, 50-70% and 30-50% of the injected dose after 7 min, 1 h, and 4 h, respectively. Since other tissues did not account for the balance and less than 5% of the injected label had been excreted into the medium after 4 h the results suggest the gradual incorporation of the metabolites into the tissues. 
  Reference    Z. Naturforsch. 45c, 1053 (1990); received April 17/June 25 1990 
  Published    1990 
  Keywords    Crustacea, Orconectes limosus, Serotonin Degradation, Hemolymph 
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 TEI-XML for    default:Reihe_C/45/ZNC-1990-45c-1053.pdf 
 Identifier    ZNC-1990-45c-1053 
 Volume    45