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'Separation o f Enantiomers' in keywords
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1995 (2)
1Author    Reinhold Tacke3, Dirk Reichel3, KurtG. Ünther5, StefanM. ErgetbRequires cookie*
 Title    The First Liquid-Chromatographic Separation of the (/?)-and (S)-Enantiomers of a Chiral Silanol, Silane and Germane  
 Abstract    The racemic mixtures of the muscarinic antagonists cyclohexyl(phenyl)(2-pyrrolidino-ethyl)silanol (sila-procyclidine, rac-1), cyclohexyl(hydroxymethyl)phenyl(2-piperidinoethyl)-silane (rac-2) and cyclohexyl(hydroxymethyl)phenyl(2-piperidinoethyl)germane (rac-3) were resolved by analytical liquid chromatography (H PLC) using chemically modified cellulose (1) or amylose (2, 3) as the chiral stationary phase. This chromatographic method was used for the quantitative determination of enantiomeric purity of the (R)-and (S)-enantiomers of 1 -3 , which were obtained by preparative resolution with chiral auxiliary agents. Further­ more, the enantiomeric purity o f these samples was established by 13C NM R studies using chiral shift reagents. According to these studies, the resolved antipodes of 1 -3 (obtained by preparative resolution) were almost enantiomerically pure [HPLC: >98.2% ee ((R)-3) to 99.4% ee ((tf)-l, (S)-l); NMR: > 97% ee]. 
  Reference    Z. Naturforsch. 50b, 568 (1995); received October 31 1994 
  Published    1995 
  Keywords    Chiral Silanol, Chiral Silane, Chiral Germane, Liquid Chromatography, Separation o f Enantiomers 
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 TEI-XML for    default:Reihe_B/50/ZNB-1995-50b-0568.pdf 
 Identifier    ZNB-1995-50b-0568 
 Volume    50 
2Author    Z. NaturforschRequires cookie*
 Title    Oligophosphan-Liganden, XL*  
 Abstract    fra/i.s-Cyclopentan-l,2-diyl-bis(dicyclohexylphosphan) und frans-Norbornan-2,3-diyl-bis(dicyclohexylphosphan): Synthese und Enantiomerentrennung. Reaktionen von [/ra/w-C5H8(PCy2)2]PtH(CH2CMe3) mit C -H-Bindungen unter achiralen und chiralen Bedingungen O ligophosphine Ligands, XL**. rra«s-C yclopentane-l ,2-diyl-bis(dicyclohexylphosphine) and rra/is-N orbornane-2,3-diyl-bis(dicyclohexylphosphine): Synthesis and Separation of E nantiom ers. R eactions of [rra/i5-C5H 8(P C y2)2]P tH (C H 2C M e3) with C -H Bonds u nder A chiral and Chiral Conditions A n d re a S aare3, Lutz D ahlenburg5 * The bis(dicyclohexylphosphines) rra/i5-C5H8(PCy2)2 (1) and /ratts-C7H 10(PCy2) 2 (11) 
  Reference    Z. Naturforsch. 50b, 1009—1017 (1995); eingegangen am 11. Januar 1995 
  Published    1995 
  Keywords    Chiral Bis(phosphine), Separation o f Enantiomers, Platinum Complexes, Activation of C -H 
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 DEBUG INFO      
 TEI-XML for    default:Reihe_B/50/ZNB-1995-50b-1009.pdf 
 Identifier    ZNB-1995-50b-1009 
 Volume    50