| | 1 | Author
| H. Eikmeier, H. J. Rehm | Requires cookie* | | | Title
| Semicontinuous and Continuous Production of Citric Acid with Immobilized Cells of Aspergillus niger  | | | | Abstract
| The citric acid excretion of Ca-alginate-immobilized cells of Aspergillus niger in batch culture decreased with a half-time of approximately 19 days. Reactivation of the biocatalysts by regenera tion in growth medium was possible, but it was followed by a submerged sporulation of the fungus, and medium was highly contaminated with free cells. Citric acid production could better be prolonged by semicontinuous cultivation with medium exchange every 7 or 14 days, respective ly. After 32 days the remaining activity in semicontinuous culture was 1.4-fold higher than in comparable batch experiments. Similar improvements were obtained with a continuous process at a dilution rate of 0.125 v/v • d, whereby medium efflux | | | |
Reference
| Z. Naturforsch. 42c, 408—413 (1987); received October 1 1986 | | | |
Published
| 1987 | | | |
Keywords
| Aspergillus niger, Immobilized Cells, Citric Acid, Semicontinuous, Continuous | | | |
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| default:Reihe_C/42/ZNC-1987-42c-0408.pdf | | | | Identifier
| ZNC-1987-42c-0408 | | | | Volume
| 42 | |
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