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1992 (1)
1Author    Ulrich SchraermeyerRequires cookie*
 Title    Effects of Chloroquine on the Photosensory Membrane Turnover and the Ultrastructure of Lysosome-Related Bodies of the Crayfish Photoreceptor  
 Abstract    The effect o f chloroquine in combination with bright light on the ultrastructure o f crayfish (Orconectes limosus R.) photoreceptors was investigated in vivo. Chloroquine had several ef­ fects upon the crayfish retina. Multivesicular bodies (M VB) that are involved in lysosom al degradation o f photosensory membrane were altered in ultrastructure. M VB frequently con­ tained smaller M VB in a state o f more advanced membrane degradation. A dditionally screen­ ing pigment-like granules appeared in MVB. MVB accumulated in and filled the retinular cell cytoplasm just proximal or distal to the basement membrane which indicated inhibition o f photosensory membrane degradation. Under chloroquine treatment rhabdom degradation appeared to be inhibited, as rhabdom diameter was less reduced under these conditions. A lso chloroquine caused accumulation o f screening pigment granules in glial cells within the lamina ganglionaris. 
  Reference    Z. Naturforsch. 47c, 420 (1992); received January 17 1992 
  Published    1992 
  Keywords    Electron M icroscopy, Chloroquine, Crayfish, Photoreceptor, Screening Pigment Granules 
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 TEI-XML for    default:Reihe_C/47/ZNC-1992-47c-0420.pdf 
 Identifier    ZNC-1992-47c-0420 
 Volume    47