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2000 (1)
1Author    Afgan Farooq3, Satoshi TaharaabRequires cookie*
 Title    Biotransformation of Two Cytotoxic Terpenes, a-Santonin and Sclareol by Botrytis cinerea  
 Abstract    Two cytotoxic terpenes, a-santonin (1) and sclareol (3) were biotransformed by a plant pathogenic fungus Botrytis cinerea to produce oxidized metabolites in high yields. a-Santonin (1) on fermentation with the fungus for ten days afforded a hydroxylated metabolite iden­ tified as llß-hydroxy-a-santonin (2) in a high yield (83%), while sclareol (3) was metabolized to epoxysclareol (4) (64%) and a new compound 8-deoxy-14,15-dihydro-15-chloro-14-hy-droxy-8,9-dehydrosclareol (5) (7%), representing a rare example of microbial halogenation. 
  Reference    Z. Naturforsch. 55c, 713—717 (2000); received May 15/June 14 2000 
  Published    2000 
  Keywords    Biotransformation, a-Santonin, Sclareol, Botrytis cinerea 
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 TEI-XML for    default:Reihe_C/55/ZNC-2000-55c-0713.pdf 
 Identifier    ZNC-2000-55c-0713 
 Volume    55