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1977 (1)
1976 (1)
1Author    HaraldA B Linke, CatherineA. ChangRequires cookie*
 Title    Physiological Effects of Sucrose Substitutes and Artificial Sweeteners on Grow th Pattern and A cid Production of Glucose-Grown Streptococcus mutans Strains in vitro  
 Abstract    The synergistic effects of four sucrose substitutes, polysorbate and five artificial sweeteners were studied in vitro on growth pattern and acid production of seven glucose-grown Streptococcus mutans strains, representing the five serological groups after Bratthall. Four distinct growth pat­ terns during glucose fermentation were observed: high rate of growth with low acid production, moderate growth rate with moderate acid production, moderate growth rate with high acid pro­ duction, and slow rate of growth with moderate acid production. Depending on the strain used, the final OD at 546 nm ranged from 0.55 to 0.99 and the final pH of the medium varied between 4.65 and 4.15. While added sucrose substitutes, with exceptions, usually enhanced growth rate, most artificial sweeteners suppressed or, at higher concentrations, even inhibited growth of S. mutans-, addition of polysorbate to the medium always increased growth rate of S. mutans signifi­ cantly. The presence of sucrose substitutes during glucose fermentation had no effect on final pH of the medium, but addition of artificial sweeteners, especially sodium saccharin, elevated final pH up to 1.8 units. The observed physiological patterns and differences within the several strains of S. mutans during glucose fermentation in vitro do not necessarily relate to the five serological groups of the species. 
  Reference    (Z. Naturforsch. 31c, 245 [1976]; received February 5 1976) 
  Published    1976 
  Keywords    Streptococcus mutans, Sweeteners, Caries, Polysorbate, Saccharin 
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 TEI-XML for    default:Reihe_C/31/ZNC-1976-31c-0245.pdf 
 Identifier    ZNC-1976-31c-0245 
 Volume    31 
2Author    H. Arald, A. B. LinkeRequires cookie*
 Title    Growth Inhibition of Glucose-Grown Cariogenic and Other Streptococci by Saccharin in vitro  
 Abstract    Sodium saccharin in concentrations from 0.02 to 20.00 m g/m l inhibits the in vitro growth of glucose-grown cariogenic and other streptococci, and suppresses, esp. at the higher concentration range, the ferm entative acid production of these m icroorganism s to acid levels much lower than the critical pH of 5.5. These observations indicate a possible caries antagonism by saccharin. 
  Reference    (Z. Naturforsch. 32c, 839 [1977]; received May 9 1977) 
  Published    1977 
  Keywords    Streptococcus m utans, Saccharin, Caries, Sweeteners, Streptococci 
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 TEI-XML for    default:Reihe_C/32/ZNC-1977-32c-0839.pdf 
 Identifier    ZNC-1977-32c-0839 
 Volume    32