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1	Author	Jürgen Van Der Bosch, Heinz Maier	Requires cookie*
	Title	Density-Dependent Growth Inhibiting Interactions between 3T3 and SV40-3T3 Cells in Mixed Cultures
	Abstract	3T3 cells are shown to reduce SV40-3T3 cell population growth in a density-dependent manner in co-cultures of 3T3 and SV40-3T3 cells. The development of this inhibitory activity roughly parallels the development of density-dependent inhibition of growth in homogeneous 3T3 control cultures. The extent of reduction of SV40-3T3 growth can be manipulated by pretreatment of 3T3 cells with a high serum concentration. SV40-3T3 growth rates are reduced by factors between 10 and 20 under optimum inhibitory conditions as compared to SV40-3T3 growth in control cultures.
	Reference	Z. Naturforsch. 34c, 272 (1979); received December 19 1978
	Published	1979
	Keywords	3T3 Cells, SV40-3T3 Cells, Growth Inhibition, Cell Interactions
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	TEI-XML for	default:Reihe_C/34/ZNC-1979-34c-0272.pdf
	Identifier	ZNC-1979-34c-0272
	Volume	34

2	Author	Jürgen Van Der Bosch, Ilse Sommer, Heinz Maier, Willy Rahmig	Requires cookie*
	Title	Density-Dependent Growth Adaptation Kinetics in 3T 3 Cell Populations Following Sudden [Ca2+] and Temperature Changes. A Comparison with SV40-3T3 Cells
	Abstract	Lowered extracellular [Ca2+ ] causes low growth rates and low stationary cell densities in 3T3 cell cultures as compared to physiological [Ca2+ ]. Under otherwise constant conditions the extra cellular [Ca2+ ] determines a stable stationary cell density, which can be readied by increase of net cell number or decrease of net cell number, depending on cell density at the time of [Ca2+ ] adjustment. SV40-3T3 cells do not show this [Ca2+] dependency. At 39 °C 3T3 and SV40-3T3 cell populations show an increased growth rate at low cell densities as compared to cell popula tions at 35 °C. Approaching the stationary density the growth rate of both cell sorts is reduced faster at 39 °C than at 35 °C, leading to lower stationary cell densities at 39 °C than at 35 °C. A temperature change from 39 °C to 35 °C or in the opposite direction can affect the stationary cell density of 3T3 cell populations only if applied before reduction of growth rate by density-dependent growth-inhibiting principles has taken place.
	Reference	Z. Naturforsch. 34c, 279 (1979); received December 19 1978
	Published	1979
	Keywords	Ca2+, Temperature, Growth Control, 3T3 Cell, SV40-3T3 Cell
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	TEI-XML for	default:Reihe_C/34/ZNC-1979-34c-0279.pdf
	Identifier	ZNC-1979-34c-0279
	Volume	34