| 1 | Author
| Kurt-Peter Raezke, Hermann Frister, Eckhard Schlimme | Requires cookie* | | Title
| Ribosylierung mono-und bicyclischer Dicarbonsäureimide Ribosylation of Mono-and Bicyclic Dicarboxylic Acid Imides  | | | Abstract
| The N-trimethylsilyl compounds of the cyclic imides derived from c/s-cyclohexan-l,2-dicar-boxylic acid, cw-4-cyclohexen-l,2-dicarboxylic acid and phthalic acid were prepared. Reaction of the N-silylated cyclic imides 2 and 10 with 1,2,3,5-tetra-O-acetyl-ß-D-ribofuranose in the presence of tin tetrachloride yielded the appropriate unusual ribonucleosides 4 and 12 whereas 14 led only to traces of the ribosylated derivative. The silylation and ribosylation sites in the aforementioned bicyclic imides were proved by "H, 13 C, and 29 Si NMR spectroscopy and compared with data found for the monocyclic imides N-succinimide and N-maleinimide. | | |
Reference
| Z. Naturforsch. 43c, 397—402 (1988); received November 26 1987/February 9 1988 | | |
Published
| 1988 | | |
Keywords
| Dicarboxylic Acid Imides, Lactam Systems, Silylation, Ribosylation, Ribonucleosides | | |
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| default:Reihe_C/43/ZNC-1988-43c-0397.pdf | | | Identifier
| ZNC-1988-43c-0397 | | | Volume
| 43 | |
2 | Author
| Eckhard Schlimme, Kirsten Schneehagen | Requires cookie* | | Title
| Ribonucleosides in Human Milk. Concentration Profiles of These Minor Constituents as a Function of the Nursing Time  | | | Abstract
| Ribonucleosides are secreted as products of cellular R N A and ribonucleotide metabolism into physiological fluids such as blood, milk and urine. Unm odified and modified ribonucleo sides have been detected in the micromolar range as minor constituents in the milk of differ ent mammals. In addition to the common nucleosides adenosine, cytidine, guanosine, inosine and uridine, modified components such as 1-methyladenosine, 1-methylguanosine, 1-methyl-inosine, N2-methylguanosine, N2-dim ethylguanosine, N 6-carbamoyl-L-threonyladenosine, pseudouridine and 5-aminoimidazole-4-carboxamide-N-ribofuranoside (A IC A R) have been identified and most of them quantified in samples of human and/or bovine and/or goat's milk. From these investigations it is known that nucleosides, in analogy to nucleotides, show a typical species-specific pattern. Longitudinal studies have been carried out to determ ine the concentration profiles of the individual ribonucleosides in the milk of humans as a function of the nursing time. | | |
Reference
| Z. Naturforsch. 50c, 105—113 (1995); received August 15/September 23 1994 | | |
Published
| 1995 | | |
Keywords
| Ribonucleosides, R NA Catabolites, Human Milk, Nursing Time | | |
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| default:Reihe_C/50/ZNC-1995-50c-0105.pdf | | | Identifier
| ZNC-1995-50c-0105 | | | Volume
| 50 | |
3 | Author
| Kurt-Peter Raezke, Eckhard Schlimme | Requires cookie* | | Title
| Ribonucleoside in Milch: Charakterisierung und Bestimmung des Konzentrationsprofils dieser minoren Komponenten über eine Laktationsperiode Ribonucleosides in Milk: Characterization and Determination of the Concentration Profile of these Minor Components throughout a Lactation Period  | | | Abstract
| The ribonucleosides adenosine, cytidine, guanosine, inosine and uridine as well as the modi fied components N 1-methyladenosine and N 6 -carbamoylthreonyladenosine were character ized and determined quantitatively as minor constituents in raw bovine milk by use of an auto mated high performance liquid chromatography system. The studies have shown that except for the colostral phase the ribonucleoside levels are constant throughout the whole lactation period. That means, there is a typical ribonucleoside pattern which is assumed to be species-specific. | | |
Reference
| Z. Naturforsch. 45c, 655 (1990); received February 23 1990 | | |
Published
| 1990 | | |
Keywords
| Bovine Milk, Colostral Phase, Lactation Period, Minor Milk Constituents, Ribonucleosides | | |
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| default:Reihe_C/45/ZNC-1990-45c-0655.pdf | | | Identifier
| ZNC-1990-45c-0655 | | | Volume
| 45 | |
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