| | 1 | Author
| JesperV. Møller, TalaatS. Mahrous, JensP. Andersen, Marc Le, Maire | Requires cookie* | | | Title
| Functional Significance of Quaternary Organization of the Sarcoplasmic Reticulum Ca2+-ATPase  | | | | Abstract
| There is both structural and functional evidence for protein-protein interaction between Ca2+-ATPase polypeptide chains in the sarcoplasm ic reticulum membrane. Studies on detergent solubilized ATPase indicate that the m onom eric form is capable o f performing a normal cycle o f ATP hydrolysis, but som e o f the m odulatory effects o f the substrates disappear after detergent solubilization. However, the necessity o f protein-protein interactions for the Ca2+ transport function remains unclarified. A new approach is described, em ploying A TPase reconstituted with a large excess o f phospholipid, which m ay help to resolve this question. | | | |
Reference
| Z. Naturforsch. 37c, 517—521 (1982); received February 4 1982 | | | |
Published
| 1982 | | | |
Keywords
| Sarcoplasmic Reticulum Ca2+-ATPase, Protein-Protein Interactions, Reconstitution | | | |
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| default:Reihe_C/37/ZNC-1982-37c-0517.pdf | | | | Identifier
| ZNC-1982-37c-0517 | | | | Volume
| 37 | |
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