| 1 | Author
| M. Wink, T. Hartmann, L. Witte | Requires cookie* | | Title
| Enzymatic Synthesis of Quinolizidine Alkaloids in Lupin Chloroplasts  | | | Abstract
| The enzymatic sequence responsible for the biosynthesis o f tetracyclic quinolizidine alkaloids could be localized in chloroplasts isolated from Lupinus polyphyllus leaves and L. albus seedlings by differential centrifugation. U pon feeding of cadaverine to isolated chloroplasts lupanine is produced as the m ain alkaloid. Chloroplasts treated with digitonine produce sparteine and 17-oxosparteine instead o f lupanine, thus indicating that the biosynthetic sequence is interrupted. The intermediacy of 17-oxosparteine could be confirmed since exogeneous 17-oxosparteine is con verted into lupanine by intact chloroplasts. 17-Oxosparteine synthase (see Z. N aturforsch. 34 c, 704 1979) the key enzyme of quinolizidine alkaloid biosynthesis could be solubilized from chloro plasts treated with detergents or osmotic shock. | | |
Reference
| Z. Naturforsch. 35c, 93—9 (1980); received Septem ber 26 1979 | | |
Published
| 1980 | | |
Keywords
| Quinolizidine Alkaloids, Enzymatic Synthesis, Isolated Chloroplasts, Lupinus polyphyllus | | |
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| default:Reihe_C/35/ZNC-1980-35c-0093.pdf | | | Identifier
| ZNC-1980-35c-0093 | | | Volume
| 35 | |
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