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1998 (1)
1994 (1)
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1Author    R. Maschler, C. J. Smith, J. C. Allen, H. R. MaurerRequires cookie*
 Title    Elucidation of the Different Effects of Polyamines and Other Naturally-Occurring Inhibitors of Cell Proliferation (Chalones) on T-Lymphocyte and Granulocyte Colony Growth in vitro  
 Abstract    Using T-lymphocyte and granulocyte colony assays with truly proliferating cells the effects of the polyamine spermine and o f other naturally-occurring inhibitors of cell proliferation have been differentiated. It has been confirmed that spermine, in the presence o f fetal calf serum, is a potent inhibitor of cell proliferation. This inhibition could be reversed by the addition o f either 3-hydroxybenzyl-oxyamine or 4-bromo-3-hydroxybenzyl-oxyamine, both of which are inhibitors of the polyamine oxidase. In comparison, fractions isolated from calf thymus were shown to inhibit lymphocyte, but not granulocyte colony growth, indicating their tissue specificity and lymphocyte chalone activity. Further this inhibition was not reversed by polyamine oxidase inhibitors demonstrating that polyamines were not the inhibitory principles in this preparation. 
  Reference    Z. Naturforsch. 38c, 74—7 (1983); received February 24/August 24 1982 
  Published    1983 
  Keywords    Polyamines, Lymphocyte Responsiveness, Polyamine Oxidase Inhibitors, Lymphocyte Chalone 
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 TEI-XML for    default:Reihe_C/38/ZNC-1983-38c-0074.pdf 
 Identifier    ZNC-1983-38c-0074 
 Volume    38 
2Author    Kiriakos Kotzabasis, Horst SengerRequires cookie*
 Title    Free, Conjugated and Bound Polyamines during the Ceil Cycle in Synchronized Cultures of Scenedesmus obliquus  
 Abstract    The levels of free, conjugated and bound polyamines (PA) were analyzed during the cell cycle of the synchronized unicellular green alga Scenedesmus obliquus. The polyamines putrescine (PUT) and spermidine (SPD) in their free and conjugated forms accumulated per cell to a maximum in the cell cycle at about the 16 th hour after onset of illumination. The polyamines bound to macromolecules and membrane systems showed an additional peak around the 8-10 th hour of the cell cycle. The possible role of the different forms of poly­ amines in DNA replication, mitosis, cell division and development of the photosynthetic apparatus is discussed. 
  Reference    Z. Naturforsch. 49c, 181—185 (1994); received December 31993 
  Published    1994 
  Keywords    Cell Cycle, Polyamines, Putrescine, Spermidine, Scenedesmus 
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 TEI-XML for    default:Reihe_C/49/ZNC-1994-49c-0181.pdf 
 Identifier    ZNC-1994-49c-0181 
 Volume    49 
3Author    Kiriakos Kotzabasis3, D. Ieter, D. Örnem AnnbRequires cookie*
 Title    Differential Changes in the Photosynthetic Pigments and Polyamine Content during Photoadaptation and Photoinhibition in the Unicellular Green Alga Scenedesmus obliquus  
 Abstract    In the unicellular green alga Scenedesmus obliquus the level o f photoinhibition and the recovery of the cells after reversal to the initial light conditions in relation to the pre-photo-adaptation of the culture to low, medium and high light intensity was determined. The changes in the photosynthetic pigment content and in the intracellular polyam ine concentra­ tion allowed to distinguish between photoadaptation and photoinhibition. In particular, the level of chlorophylls, xanthophylls and carotenoids decreased inversely proportional to the light intensity applied during photoadaptation, whereas their concentrations remained con­ stant during photoinhibition. The violaxanthin/zeaxanthin and the loroxanthin/lutein cycle work only under photoinhibitory conditions, but not under photoadaptive premises. Changes in the level of these carotenoids in relation to the changes in the photosynthetic apparatus during photoadaptation are discussed. In addition, it was found that the intracellular polya­ mine level increased only under stress conditions, i. e. during photoinhibition, and decreased during recovery of the cells after reversal to the initial light conditions. The increase of the putrescine level during photoinhibition is inversely proportional to the light intensity used for pre-adaptation. This rise of the polyamine level in the cells photoadapted to high light conditions is an additional indication for the finding that photoadaptation and photoinhibi­ tion are different phenomena which are clearly distinguishable from each other. Finally, the changes of the chlorophyll, violaxanthin, zeaxanthin, loroxanthin, lutein and polyamine levels under photoadaptation in high light intensity (50 W m '2) in relation to the range of photo­ adaptation in Scenedesmus obliquus are discussed. 
  Reference    Z. Naturforsch. 53c, 833—8 (1998); received May 8/June 15 1998 
  Published    1998 
  Keywords    Polyamines, Photosynthetic Apparatus, Photoinhibition, Photoadaptation, Scenedesmus obliquus 
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 TEI-XML for    default:Reihe_C/53/ZNC-1998-53c-0833.pdf 
 Identifier    ZNC-1998-53c-0833 
 Volume    53