| 1 | Author
| H.Wolfgang Heger, HorstW. Peter | Requires cookie* | | Title
| Effects of Phospholipids in the Action of Acetyl-CoA Carboxylase from Rat Liver  | | | Abstract
| Acetyl-CoA carboxylase (E.C. 6.4.1.2) was isolated from rat liver. The purified enzyme con tains phospholipids with a rather large amount of phosphatidylinositol (26%). Incubation of the purified acetyl-CoA carboxylase with phospholipase A2 (E.C. 3.1.1.4) or with phospholipase D (E.C. 3.1.1.4) diminishes the phospholipid content by 70%, this treatment leading to a complete inactivation of the enzyme. After removal of the phospholipases, the lipid-depleted enzyme can be reactivated to a certain degree by incubation with a phospholipid extract from rat liver, with phosphatidylinositol alone, or with serum albumin. | | |
Reference
| (Z. Naturforsch. 32c, 97 [1977]; received October 12 1976) | | |
Published
| 1977 | | |
Keywords
| Phospholipids, Acetyl-CoA Carboxylase, Rat Liver, Fatty Acid Synthesis, Phospholipases | | |
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| default:Reihe_C/32/ZNC-1977-32c-0097.pdf | | | Identifier
| ZNC-1977-32c-0097 | | | Volume
| 32 | |
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