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'Phospholipids' in keywords Facet   Publication Year 1988  [X]
Facet   section ZfN Section C  [X]
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1Author    Rolf-M ServussRequires cookie*
 Title    Spontaneous Formation of Giant Phospholipid Vesicles  
 Abstract    The spontaneous formation of giant (diameter > 10 pm) vesicles from a number of phospholi-pids in excess aqueous solution has been studied by light-microscopy. Electrically neutral as well as charged phospholipids swell to form giant vesicles only if the lipids are in the fluid phase. This shows that electrostatic repulsion alone cannot explain the spontaneous formation of giant vesi-cles. The results confirm the suggestion that steric forces between extended membranes play a significant part in this process. 
  Reference    Z. Naturforsch. 43c, 938—947 (1988); received July 1/August 8 1988 
  Published    1988 
  Keywords    Vesicles, Phospholipids, Membrane Interaction 
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 TEI-XML for    default:Reihe_C/43/ZNC-1988-43c-0938.pdf 
 Identifier    ZNC-1988-43c-0938 
 Volume    43 
2Author    DouglasL. DorsetRequires cookie*
 Title    How Different are the Crystal Structures of Chiral and Racemic Diacylphosphatidylethanolamines?  
 Abstract    Both chiral and racemic phosphatidylethanolamines are known to crystallize in a similar poly-morphic form with nearly the same lamellar spacing; yet published lamellar X-ray diffraction intensity data for those materials do not agree with one another, even though the peak positions in Patterson maps are nearly the same. Translational structural searches based on the crystal struc-ture of the racemic compound also lead to similar packing models with both data sets, although the agreement between model and observed data is poor for the chiral compound. A separate analysis of L-DMPE based on lamellar electron diffraction data again leads to a similar lamellar structure with a better agreement between calculated and observed structure factors. The major difference seen for enantiomeric vs. racemic compounds is that, for the racemic lipid, the lateral unit cell spacings are about 3% larger than the chiral form, perhaps indicating a more stable hydrogen bonding network, in agreement with the higher melting point of the racemic compound. Attempts to explain this difference with other head group conformations, however, have not yet produced an improved structural model. 
  Reference    Z. Naturforsch. 43c, 319—327 (1988); received November 20 1987 
  Published    1988 
  Keywords    Phospholipids, X-Ray Diffraction, Electron Diffraction 
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 TEI-XML for    default:Reihe_C/43/ZNC-1988-43c-0319.pdf 
 Identifier    ZNC-1988-43c-0319 
 Volume    43 
3Author    M. Suwalsky, L. Gimenez, V. Saenger, F. NeiraRequires cookie*
 Title    X-Ray Studies on Phospholipid Bilayers. VIII. Interactions with Chlorpromazine * HCl  
 Abstract    Chlorpromazine is a widely used phenothiazine tranquilizer known to alter the shape of normal erythrocytes and their osmotic fragility. In order to understand the nature of the interactions chlorpromazine • HCl (CPZ HCl) was made to interact with phospholipid bilayers formed by dimyristoylphosphatidylethanolamine (DMPE) and dimyristoylphosphatidylcholine (DMPC). This study was carried out by X-ray diffraction on crystalline powders of various molar mixtures of CPZ -HCl with DMPE and DMPC, with and without water. It was found that CPZ -HCl significa-tively affects the bilayer structure of DMPC in the presence of water, but not that of DMPE. 
  Reference    Z. Naturforsch. 43c, 742—748 (1988); received March 23/June 13 1988 
  Published    1988 
  Keywords    X-Ray Diffraction, Phospholipid, Bilayer, Chlorpromazine @BULLET HCl 
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 TEI-XML for    default:Reihe_C/43/ZNC-1988-43c-0742.pdf 
 Identifier    ZNC-1988-43c-0742 
 Volume    43