| | 1 | Author
| M. Suwalsky, M. A. Espinoza, M. Bagnara, C. P. Sotomayor | Requires cookie* | | | Title
| X-Ray and Fluorescence Studies on Phospholipid Bilayers. IX. Interactions with Pentachlorophenol  | | | | Abstract
| Pentachlorophenol (PCP) is a widely used and highly toxic fungicide. Its toxicity is mainly expressed at the cell membrane level. It is, therefore, o f interest to test its ability to alter the lipid bilayer organization. The present study was performed by X-ray diffraction techniques on dimyristoylphosphatidylethanolam ine (D M PE) and dim yristoylphosphatidylcholine (D M P C) bilayers and by fluorescence on DM PC liposomes. These two phospholipids are re spectively found at the inner and outer monolayers o f human erythrocyte membranes. Each type o f phospholipid was made to interact with different concentrations o f the sodium form o f PCP in absence and in presence o f water. It was found that PCP significatively affected the structure o f both phospholipids, being the damage much higher in DM PC bilayers. | | | |
Reference
| Z. Naturforsch. 45c, 265 (1990); received September 18 1989 | | | |
Published
| 1990 | | | |
Keywords
| X -R ay Diffraction, Fluorescence, Phospholipid Bilayers, Pentachlorophenol, Toxicity | | | |
Similar Items
| Find | | | DEBUG INFO
| | | | | TEI-XML for
| default:Reihe_C/45/ZNC-1990-45c-0265.pdf | | | | Identifier
| ZNC-1990-45c-0265 | | | | Volume
| 45 | |
|
