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1990 (1)
1Author    M. Suwalsky, M. A. Espinoza, M. Bagnara, C. P. SotomayorRequires cookie*
 Title    X-Ray and Fluorescence Studies on Phospholipid Bilayers. IX. Interactions with Pentachlorophenol  
 Abstract    Pentachlorophenol (PCP) is a widely used and highly toxic fungicide. Its toxicity is mainly expressed at the cell membrane level. It is, therefore, o f interest to test its ability to alter the lipid bilayer organization. The present study was performed by X-ray diffraction techniques on dimyristoylphosphatidylethanolam ine (D M PE) and dim yristoylphosphatidylcholine (D M P C) bilayers and by fluorescence on DM PC liposomes. These two phospholipids are re­ spectively found at the inner and outer monolayers o f human erythrocyte membranes. Each type o f phospholipid was made to interact with different concentrations o f the sodium form o f PCP in absence and in presence o f water. It was found that PCP significatively affected the structure o f both phospholipids, being the damage much higher in DM PC bilayers. 
  Reference    Z. Naturforsch. 45c, 265 (1990); received September 18 1989 
  Published    1990 
  Keywords    X -R ay Diffraction, Fluorescence, Phospholipid Bilayers, Pentachlorophenol, Toxicity 
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 TEI-XML for    default:Reihe_C/45/ZNC-1990-45c-0265.pdf 
 Identifier    ZNC-1990-45c-0265 
 Volume    45