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'Peptides' in keywords Facet   Publication Year 1987  [X]
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1987[X]
1Author    Ernst Bayer, Heribert Hellstern, Heiner EcksteinRequires cookie*
 Title    Synthese von immobilisierten Peptidfragmenten an Polystyrol-Polyoxyethylen zur Affinitätschromatographie Synthesis of Immobilized Peptide Fragments on Polystyrene-Polyoxyethylene for Affinity Chromatography  
 Abstract    Polystyrene-polyoxyethylene craft copolymers have been used for step-wise peptide synthesis. After completion of synthesis the protecting groups are cleaved under acidic conditions, where the polymer-peptide bond is stable. These gels in comparison to polystyrene peptide gels, show better properties for applications in affinity chromatography as well as synthesis on solid supports, because the advantageous properties of polystyrene beads are combined with the excellent spacer behavior of polyoxyethylene chains (mobility, solvation by water and organic solvents). Peptide gels with polylysine sequences have been synthesized as highly selective stationary phases for the separation of the homologous oligo desoxyribonucleotides (d7)n with n = 1—3. The principal possibilities of these gels for affinity chromatography 
  Reference    Z. Naturforsch. 42c, 455—460 (1987); received December 1 1986 
  Published    1987 
  Keywords    birthday Affinity Chromatography, Immobilization, Liquid-Solid-Phase, Peptides, Synthesis 
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 TEI-XML for    default:Reihe_C/42/ZNC-1987-42c-0455.pdf 
 Identifier    ZNC-1987-42c-0455 
 Volume    42 
2Author    Karl Folkers, Cyril Bowers, Xiao Shao-Bo, Pui-Fun, Louisa Tang, Minoru Kubota, Janusz Stepinski, Teresa KubiakRequires cookie*
 Title    Activities of Antagonists of the Luteinizing Hormone Releasing Hormone with Emphasis on Positions 1, 5 and 6 and on Positions 1, 2 and 3  
 Abstract    Analogs of the luteinizing hormone releasing hormone (LHRH) which are antagonists for controlling ovulation require potency and negligible release of histamine as a side effect. Forty analogs were designed, synthesized and bioassayed in two groups with emphasis upon positions 1, 5 and 6 and upon positions 1, 2 and 3. N-Ac-D-2-Nal 1 , D-pClPhe 2 , D-3-Pal 3 , Ser 4 , Tyr 5 . D-Lys 6 , 
  Reference    (Z. Naturforsch. 42b, 101—106 [1987]; received July 18 1986) 
  Published    1987 
  Keywords    Luteinizing Hormone Releasing Hormone, a«f/-Ovulatory Activity, Peptide, Antagonist, Histamine Release 
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 TEI-XML for    default:Reihe_B/42/ZNB-1987-42b-0101.pdf 
 Identifier    ZNB-1987-42b-0101 
 Volume    42