| | 1 | Author
| A. Marston, E. Hecker | Requires cookie* | | | Title
| Structure-Activity Relationships of Polyfunctional Diterpenes of the Tigliane Type, V* Preparation and Irritant Activities of Amino Acid and Peptide Esters of Phorbol  | | | | Abstract
| The synthesis of a series of 12-O-amino acyl-and 12-0-peptidyl-13-acetate and -13,20-diacetate esters of the tetracyclic diterpene alcohol phorbol is described. These esters, which include amino acid moieties with both N-protected and free amino functions, were all tested for irritant activity on mouse ear. The highest activities were observed for esters with N-9-fluorenylmethyloxycarbonyl-protected leucine and 11-aminoundecanoic acid. | | | |
Reference
| Z. Naturforsch. 38b, 1015—1021 (1983); received March 28 1983 | | | |
Published
| 1983 | | | |
Keywords
| Amino Acids, Peptides, Phorbol Esters, Irritants, Tumour Promoters | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1015.pdf | | | | Identifier
| ZNB-1983-38b-1015 | | | | Volume
| 38 | |
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