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'Partial Hepatectomy' in keywords
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1981 (1)
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1978 (1)
1Author    Wolf Strecker, Siegfried Silz, Gerhard Ruhenstroth-Bauer, Ingolf BöttgerRequires cookie*
 Title    Insulin und Glukagon im Blutplasma teilhepatektomierter Ratten Insulin and Glucagon in the Blood Plasma of Partial Hepatectomized Rats  
 Abstract    U p to 4 weeks after partial hepatectomy the concentrations o f im m unoreactive insulin and glucagon in the blood plasma of rats were determined. Furtherm ore we m easured the activity of acid phosphatase in the serum, the concentration of cyclic AM P in liver cells, the activities of acid phosphatase in whole liver cells and in the cytosol of liver cells after partial hepatectomy. 2 h after partial hepatectom y there was a decline of the concentration o f insulin in the plasm a to about 13% of the initial value. 12 h after surgery a 5-fold increase of glucagon was found in the plasma. Shortly after this cyclic AMP reached its highest concentration. The activity of acid phosphatase in the whole liver cells and in the cytosol decreases slightly in the first 24 h after surgery whereas there is an increase o f the activity of acid phosphatase in the serum. 
  Reference    Z. Naturforsch. 35c, 65—7 (1980); eingegangen am 2. M ärz/2. August 1979 
  Published    1980 
  Keywords    Rat, Partial Hepatectomy, Blood Plasma, Glucagon, Insulin 
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 TEI-XML for    default:Reihe_C/35/ZNC-1980-35c-0065.pdf 
 Identifier    ZNC-1980-35c-0065 
 Volume    35 
2Author    W. Strecker, G. Ruhenstroth-B, Auer, I. Böttger, H. W. PabstRequires cookie*
 Title    Glucagon-Like Immunoreactivity (GLI) in Blood Plasma of Partially Hepatectomized Rats  
 Abstract    The concentration o f substances with glucagon-like immunoreactivity (GLI) was determined in arterial blood plasma o f rats up to 4 weeks after partial hepatectomy. 10 h following surgery a more than 18-fold increase in GLI + glucagon immunoreactivity could be observed. About 2/3 of the maximum activity seems to be of non pancreatic origin. The levels returned to normal about 22 h after surgery. 
  Reference    Z. Naturforsch. 36c, 464 (1981); received December 2 1980 
  Published    1981 
  Keywords    Partial Hepatectomy, Glucagon-Like Immunoreactivity (GLI), Glucagon Immunoreactivity 
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 TEI-XML for    default:Reihe_C/36/ZNC-1981-36c-0464.pdf 
 Identifier    ZNC-1981-36c-0464 
 Volume    36 
3Author    R. Strasser, M. VolmRequires cookie*
 Title    Untersuchungen über spezifische Einflüsse des Serums und Lebercytoplasmas auf den [3H]TTP-Einbau isolierter Leberzellkerne Studies on the Specific Effects of Serum and Cytoplasm of the Liver on the [3H]TTP-Incorporation of Isolated Liver Nuclei  
 Abstract    Previous authors have described that liver cytoplasm and serum from partially hepatectomized rats stimulate the DNA synthesis of isolated nuclei of liver cells. The aim of our investigation was to prove whether such stimulating effects are part of a specific regulation of growth. The sera and the cytoplasm supernatant 105 000 Xg) were isolated at several intervals after partial hepatectomy and laparotomy and were tested on isolated nuclei of liver cells from adult rats partially hepatectomized 20 hours before. The supernatants isolated at 8 and 16 hours after both partial hepatectomy and laparotomy have a significant stimulatory effect on the [3H]TTP-uptake by nuclei. The presence of serum (10%) causes a general elevation (75%) of the [3H]TTP-uptake by isolated nuclei. The sera isolated 4 to 12 hours after operation from both partially hepatectomized and laparotomized rats have an additional stimulatory effect on the [3H] TTP-uptake synthes of nuclei. In no case did the sera and liver cytoplasm of partially hepatectomized rats have a significantly different and therefore "specific" effect on the nuclear DNA synthesis. Additional experiments showed that frozen and thawed nuclei of liver cells respond only to the nutritive power but not to the stimulatory effects of the sera. Thus, thawed nuclei cannot be used for growth investigations. 
  Reference    Z. Naturforsch. 33c, 219 (1978); eingegangen am 5. September 1977/25. Januar 1978 
  Published    1978 
  Keywords    Isolated Liver Nuclei, Partial Hepatectomy, [3H] TTP-Incorporation, Serum, Cytoplasm 
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 TEI-XML for    default:Reihe_C/33/ZNC-1978-33c-0219.pdf 
 Identifier    ZNC-1978-33c-0219 
 Volume    33 
4Author    Paul Miller, W. Alfried, A. Linden, Claudio NicoliniRequires cookie*
 Title    Physico-Chemical Studies of Isolated Chromatin Compared with in situ Chromatin after Partial Hepatectomy in the Rat  
 Abstract    Chromatin was isolated from rat liver cells at 0, 3, 5, 11, 18 and 24 h following partial hepa­ tectomy. Consistent with findings in cultured cells stimulated to proliferate, there was an increase in chromatin molar ellipticity measured at 276 nm, and a decrease in thermal stability 3 to 8 h after surgery. These events occured prior to the onset of DNA synthesis. These early changes be­ tween non-proliferating (G0) and proliferating (Gj) cells, as well as later chromatin conformational changes observed at S and G2 phases, mimic changes in template activity. Results with sheared and unsheared chromatin (both with in vitro and in vivo systems) prove that structural and functional changes can be caused by even the slightest shearing during chromatin preparation, suggesting the loss of native chromatin organization. To eliminate this problem, ex­ periments were also conducted using chromatin in situ. A flow cytometer (FCM) was used to study unfixed liver cell suspensions stained with ethidium bromide (EB). Fluorescence was mea­ sured in the green spectral range after addition of increasing amounts of EB. Experimental evidence is provided that the same alteration in chromatin conformation can be best detected using low molar ratios of EB per unit DNA due to greater fluorescence emission in Gj respect to G0 cells. These correlated studies demonstrate that the same changes controlling chromatin organization in situ are detected also in the tertiary-quaternary structure of "isolated" chromatin. These changes in chromatin conformation are macromolecular events related to cell proliferation both at the G0 —Gt and Gt —S transitions. 
  Reference    Z. Naturforsch. 34c, 442 (1979); received December 15 1978/February 19 1979 
  Published    1979 
  Keywords    Isolated Chromatin, Partial Hepatectomy, Molar Ellipticity, Thermal Stability, Flow Cytometry 
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 TEI-XML for    default:Reihe_C/34/ZNC-1979-34c-0442.pdf 
 Identifier    ZNC-1979-34c-0442 
 Volume    34