| 1 | Author
| Magdalena Karamać, Ryszard Amarowicz | Requires cookie* | | Title
| Inhibition of Pancreatic Lipase by Phenolic Acids -Examination in vitro  | | | Abstract
| The influence of addition 2, 4, 6, 8, and 10 [j .m of ben zoic and cinnamic acids and selected phenolic acids (sali cylic, /^-hydroxybenzoic, gentisic, protocatechuic, vanil lic, syringic, o-coumaric, p-coumaric, caffeic, ferulic, sinapic) on the activity of pancreatic lipase was exam ined in vitro. The strongest inhibition activities were ob served with caffeic, ferulic and benzoic acid, while si napic and gentisic acids produced the lowest inhibition. benzoic, /^-hydroxybenzoic, gentisic, vanillic, syrin gic, cinnamic, o-coumaric, p-coumaric, caffeic, fer ulic, sinapic (all from Sigma). Chemical structures of the compounds m entioned above are described in Fig. 1. o Acids: Benzoic Salicylic p-Hydroxybenzoic Gentisic Protocatechuic Vanillic Syringic R: 4-H R: 2-OH R: 4-OH R: 2,5-di-OH R: 3,4-di-OH R: 3-OCH3, 4-OH R: 3,5-di-OCH3, 4-OH | | |
Reference
| Z. Naturforsch. 51c, 903—905 (1996); received May 28/September 4 1996 | | |
Published
| 1996 | | |
Keywords
| Phenolic Acids, Pancreatic Lipase, Inhibition | | |
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| default:Reihe_C/51/ZNC-1996-51c-0903_n.pdf | | | Identifier
| ZNC-1996-51c-0903_n | | | Volume
| 51 | |
2 | Author
| Zbigniew Sroka3, Marian Jurzystab, Joanna Tylcz3, Halina Rzadkowska-Bodalska3 | Requires cookie* | | Title
| Stimulation of Pancreatic Lipase Activity by Saponins Isolated from Medicago sativa L  | | | Abstract
| Saponins isolated from Medicago sativa L. appeared to stimulate lipolytic activity and did not influence amylolytic or proteolytic activity of Neopancreatinum (extract of pancreatic enzymes: lipase, proteases and amylases). Saponins isolated from the aerial part of Medicago sativa L. were demonstrated to stimulate lipase activity more effectively than saponins sepa rated from the root of this plant. When saponins were treated with 0.02 m HC1 at 37 °C for 1 hour their lipase stimulation ability did not change. The saponins stimulated Neopancreatinum lipolytic activity more in tensively in the presence of sodium cholate. | | |
Reference
| Z. Naturforsch. 52c, 235—239 (1997); received October 29/December 18 1996 | | |
Published
| 1997 | | |
Keywords
| Saponins, Medicago sativa L, Pancreatic Lipase, Lipase Stimulation | | |
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| default:Reihe_C/52/ZNC-1997-52c-0235.pdf | | | Identifier
| ZNC-1997-52c-0235 | | | Volume
| 52 | |
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