1 | Author | Rüdiger Hofm, H. Artm, Ut Follmann | Requires cookie* |
Title | Bleom ycin-Iron C om plex and Oxygen Activate Algal R ibonucleotide Reductase ![]() | ||
Abstract | Ribonucleotide reductase of green algae (Scenedesmus obliquus) is a radical-containing enzyme which rapidly loses activity under anaerobic conditions. Reactivation in the presence of air is enhanced by 10 |j.m iron(II)-bleomycin chelate. The reaction lends new biochemical potential to the antibiotic and should be valuable in mechanistic studies of ribonucleotide reduction. | ||
Reference | Z. Naturforsch. 40c, 919—921 (1985); received August 22 1985 | ||
Published | 1985 | ||
Keywords | Bleomycin, Deoxyribonucleotide Synthesis, Iron, Oxygen Dependence, Ribonucleotide Reduction, Scenedesmus obliquus | ||
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