| | 1 | Author
| M. Ichaela, W. Ilhelm, W. Olfgang Saak, H. Enry Strasdeit | Requires cookie* | | | Title
| Phenylmercury Chloride: Its Single-Crystal X-Ray Structure and Some Aspects of its Biological Chemistry  | | | | Abstract
| A single crystal of phenylmercury chloride (PhHgCl) was obtained by serendipity from a solution of diphenylmercury (HgPh2) and dihydrolipoic acid in tetrahydrofuran / carbon tetrachloride. The crystal structure of PhHgCl is pseudotetragonal. It is best described in the orthorhombic space group Cmma with a = 6.856(1), b = 6.882(1), c = 14.309(2) A (at 193 K), and Z = 4. The Cl-Hg-C moiety of the PhHgCl moleculeois exactly linear. The bond lengths at the Hg atom are Hg-Cl 2.345(2) and Hg-C 2.044(9) Ä. In the crystal, the molecules are arranged in double layers parallel to the a,b plane. In a model medium for the gastric juice (0.1 M DC1 in D 20 / [Dg]dioxan, 37 °C), HgPh2 reacts to form PhHgCl. HgCl2, which would result from complete dearylation, cannot be isolated from the reaction mixture. However, it appears that a small equilibrium concentration of HgCl2 may be present, because on addition of 1,4,7-trithiacyclononane (ttcn) and diethyl ether, the dichloride can be trapped as solid [Hg(ttcn)2][HgCl4]. We estimate that after oral uptake of HgPh2 20 -90% are transformed into PhHgCl in the stomach after 30 min. In tro d u ctio n | | | |
Reference
| (Z. Naturforsch. 55b, 35—38 [2000]; received October 18 1999) | | | |
Published
| 2000 | | | |
Keywords
| Acidolysis, Bioinorganic Chemistry, Crystal Structure, Mercury, Organomercury Compounds | | | |
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| ZNB-2000-55b-0035 | | | | Volume
| 55 | |
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