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'Organoleads' in keywords
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2001 (1)
1997 (1)
1Author    H. Alina, Kleszczyń Ska, Janusz SarapukRequires cookie*
 Title    Influence of Organic and Inorganic Ions on Organolead-Induced Hemolysis of Erythrocytes  
 Abstract    The influence of some inorganic (K +, Mg2+, and A l3+) and organic C"H2"+1 S 0 3^, n -12 and 14) ions was studied on the hemolysis of erythrocytes (RBC) caused by organolead compounds (tripropyllead -TPL, tributyllead -TBL and triphenyllead -TPhL chlorides). It was found that sulfonate anions increased the hemolytic effect induced by triorganoleads, while inorganic cations protected RBC against the triorganoleads action, especially when the latter were used at small concentrations. This protection was weaker when the concentration of organoleads increased and depended on the kind of ion. The protective efficacy sequence was like that: Mg2+ > A l3+ > K +. The less hemolytic of the triorganoleads studied was TPL. TBL was slightly more effective than TPhL. The efficacy of the sulfonate ions to increase the triorganolead chloride -induced hemolysis was practically the same for TPL and TBL. A weaker efficacy of C i2H25S03+ was observed when TPhL was used as RBC membrane modifier. 
  Reference    Z. Naturforsch. 56c, 853—856 (2001); received February 26/March 27 2001 
  Published    2001 
  Keywords    Organoleads, Erythrocytes, Hemolysis Inhibition 
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 TEI-XML for    default:Reihe_C/56/ZNC-2001-56c-0853.pdf 
 Identifier    ZNC-2001-56c-0853 
 Volume    56 
2Author    H. Kleszczyńska, J. Hładyszowski, H. Pruchnik, S. PrzestalskiRequires cookie*
 Title    Erythrocyte Hemolysis by Organic Tin and Lead Compounds  
 Abstract    The effect of trialkyllead and trialkyltin on pig erythrocyte hemolysis has been studied and compared. The results o f experiments showed that the hemolytic activity o f organoleads increases with their hydrophobicity and follows the sequence: triethyllead chloride < tri-n-propyllead chloride < tributyllead chloride. And similarly in the case of organotins: triethyltin chloride < tri-n-propyltin chloride < tributyltin chloride. Comparison of the hemolytic activity of organoleads and organotins indicates that the lead compounds exhibit higher hemolytic activity. The methods of quantum chemistry allowed to determine the maximum electric potential of the ions R3Pb+ and R3Sn+, and suggest a relationship betw een the potential and toxicity. 
  Reference    Z. Naturforsch. 52c, 65—6 (1997); received August 9/October 7 1996 
  Published    1997 
  Keywords    Organoleads, Organotins, Erythrocyte Membrane, Hemolysis, Electric Potential 
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 TEI-XML for    default:Reihe_C/52/ZNC-1997-52c-0065.pdf 
 Identifier    ZNC-1997-52c-0065 
 Volume    52