| | 1 | Author
| Gerhard Bringmanna, Doris Feineis3, Ralph Brückner, Eva-Maria Petersb, Karl Petersb | Requires cookie* | | | Title
| 2-Hexanoyl-l-tribromomethyl-l,2,3,4-tetrahydro-/?-carboline: Crystal Structure Analysis of a Potent Inhibitor of Complex I of Mitochondrial Respiration  | | | | Abstract
| The molecular structure of the title com pound 2-hexanoyl-l-tribromomethyl-l,2,3,4-tetra-hydro-/3-carboline (3), a potent inhibitor of complex I of the mammalian mitochondrial respi ratory chain, has been studied by single-crystal X-ray diffraction analysis. In the crystal, two heterochiral molecules of 3 (i.e., one R-and one S-configured molecule each) were found to be connected with one other in pairs via two intermolecular hydrogen bonds [0(215) • • • H(212)' and 0(215)' • • • H(212)] to form an overall achiral 'dimeric' subunit. | | | |
Reference
| (Z. Naturforsch. 55b, 94—99 [2000]; received O ctober 21 1999) | | | |
Published
| 2000 | | | |
Keywords
| Crystal Structure, Bromal-Derived Tetrahydro-ß-carbolines Mitochondrial Respiration, Parkinson's Disease, Neurotoxicity | | | |
Similar Items
| Find | | | DEBUG INFO
| | | | | TEI-XML for
| default:Reihe_B/55/ZNB-2000-55b-0094.pdf | | | | Identifier
| ZNB-2000-55b-0094 | | | | Volume
| 55 | |
|
