| 1 | Author
| Ümmühan Dodofp, Nurcan Özdemirb, Milka Karacanb, Ch, SpiroM. Georgievac, MiglenaE. Konstantinov0, Stefanova6 | Requires cookie* | | Title
| Nicolay I  | | | Abstract
| Three novel Schiff bases: salicylaldehyde methanesulfonylhydrazone (1), 2-hydroxyaceto-phenone methanesulfonylhydrazone (2) and 2-hydroxy-1-naphthaldehyde methanesulfonylhy drazone (3) have been synthesized. Compounds 1-3, as well as acetone methanesulfonylhydra zone (4) have been characterized by TLC, 'H NMR and IR spectra. The spectroscopic results for 1-3 have revealed the presence of an intramolecular hydrogen bond between the hydroxyl group and the imine N atom. The conformational isomerism of 1-4 with respect to the rota tions around the SN and NN bonds have been studied by the method of molecular mechanics. Compounds 1-4 and methanesulfonylhydrazine exhibit antibacterial and cytotoxic effects. | | |
Reference
| Z. Naturforsch. 54b, 1553—1562 (1999); received July 31 1999 | | |
Published
| 1999 | | |
Keywords
| Schiff Bases, Methanesulfonylhydrazine, 'H NMR Data, M olecular Mechanics, Cytotoxic Activity | | |
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| default:Reihe_B/54/ZNB-1999-54b-1553.pdf | | | Identifier
| ZNB-1999-54b-1553 | | | Volume
| 54 | |
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