| | 1 | Author
| Giuseppe Colacicco, A. Rthur, A. Pilla | Requires cookie* | | | Title
| Electromagnetic M odulation of Biological Processes: ATPase Function and D NA Production by Raji Cancer Cells in vitro  | | | | Abstract
| Addition o f either ATP or ouabain to the culture m edium markedly depressed thym idine incorporation into D N A in Raji cells. The electrom agnetic field, pulsating at very low frequency, did not affect D N A synthesis in normal culture m edia nor did it alter its ouabain-inhibition, but it partially reversed the ATP-inhibition. In spite o f the presence o f ATP, ouabain prevented stimulation o f ATPase and D N A synthesis by the field. Although no m echanism is known for the action o f either ATP or the field, the results may be interpreted in light o f existing speculations. In the absence o f the field, external ATP may go into an ATP pool that either blocks ATPase or feeds adenyl cyclase, which hinders D N A synthesis. In contrast, the electrom agnetic field may either turn o ff adenyl cyclase or sim ply stim ulate the | | | |
Reference
| Z. Naturforsch. 38c, 468—470 (1983); received N ovem ber 29 1982/M arch 16 1983 | | | |
Published
| 1983 | | | |
Keywords
| Pulsating Electromagnetic Fields, M embrane Coupling, Plasma M embrane ATPases, D N A Synthesis, Cell Proliferation | | | |
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| default:Reihe_C/38/ZNC-1983-38c-0468.pdf | | | | Identifier
| ZNC-1983-38c-0468 | | | | Volume
| 38 | |
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