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1979 (1)
1Author    Giuseppe Colacicco, A. Purba, K. Ray, MukulK. Basu, M. Urray, W. Ittner, RobertM. RosenbaumRequires cookie*
 Title    Cultured Lung Cells: Interplay Effects of Beta-Mimetics, Prostaglandins and Corticosteroids in the Biosynthesis of Dipalmitoyl Lecithin  
 Abstract    Cell lines derived from type II lung cells were used to study interplays of substances affecting incorporation of labeled precursors [1-14C] palmitate and [methyl-3H] choline into phosphatidyl choline. Ethanol stimulated markedly biosynthesis of dipalmitoyl phosphatidyl choline in cloned rabbit lung cells; the stimulating action of ethanol was reduced very much by cortisol and less by ritodrine. In the presence of 0.1 m m isoproterenol, two prostaglandins, E2 and F2a, caused marked depressions in the incorporation of both precursors by cell line A 549 derived from human lung adenocarcinoma. One concluded that among the agents studied, ethanol and cortisol are potent antagonists, and so were also the prostaglandins and isoproterenol. 
  Reference    Z. Naturforsch. 34c, 101 (1979); received October 6 1978 
  Published    1979 
  Keywords    Ethanol Metabolism, Beta-Stimulants, Lung Type II Cells, Pulmonary Surfactant, Cortisol 
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 TEI-XML for    default:Reihe_C/34/ZNC-1979-34c-0101.pdf 
 Identifier    ZNC-1979-34c-0101 
 Volume    34