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1985 (1)
1975 (1)
1Author    Jan Diek, Van Mansvelt, Ferdinand AmonsRequires cookie*
 Title    Inquiry into the Limits of Biological Effects of Chemical Compounds in Tissue Culture, I Low Dose Effects of Mercuric Chloride  
 Abstract    Experiments were designed to investigate the low-dose side of the so-called dose-effect relation of mercuric chloride on the proliferation of a murine lymphoblastic cell strain (MB V ia). Three concentration ranges, from 0.9 x 10~5 m to 0.9 x 10-18 m, from 0.9 x 10-12 m to 0.9 x 10-25 m , and from 0.9 x 10-15 M to 0.9 x IO-21 M, in which the concentration decreased stepwise by a factor 10, were studied in 61, 74 and 58 experimental repetitions, respectively. In the first range, the concentrations 0.9 x 10-5 M and 0.9 x 10~6 m HgCl2 proved to be definite­ ly toxic as was expected. However, also 0.9 x 10—16 m and 0.9x i10~17m appeared to be growth-inhibiting, the latter results being confirmed in the second and the third concentration ranges. These differences in cell growth were statistically significant. 
  Reference    (Z. Naturforsch. 30c, 643—649 [1975]; received February 19/April H6 1975) 
  Published    1975 
  Keywords    Mercurichloride, Low-Dose Effect, Drug^Effect Relation, Serial Dilution, Tissue Culture 
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 TEI-XML for    default:Reihe_C/30/ZNC-1975-30c-0643.pdf 
 Identifier    ZNC-1975-30c-0643 
 Volume    30 
2Author    StephanPaul Jost, Jane Cole, BrianC. GoodwinRequires cookie*
 Title    Growth R esponse o f M ouse Lymphoma Cells to Low Concentrations o f Mercuric Chloride  
 Abstract    Three growth rate experiments involving several sam­ pling points were performed to investigate the previous finding that very low concentrations of HgCl2 inhibit the growth of murine lymphoblasts in vitro. However, results presented here do not confirm this, there being no signifi­ cant differences between the three independent growth rate experiments. 
  Reference    Z. Naturforsch. 40c, 922 (1985); received July 15/September 11 1985 
  Published    1985 
  Keywords    Mercuric Chloride, Low Dose Effect, Tissue Culture, Murine Lymphoblasts, Growth Rate Experiments 
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 TEI-XML for    default:Reihe_C/40/ZNC-1985-40c-0922_n.pdf 
 Identifier    ZNC-1985-40c-0922_n 
 Volume    40