ZfN: Search Results

1	Author	Wolf Strecker, Siegfried Silz, Gerhard Ruhenstroth-Bauer, Ingolf Böttger	Requires cookie*
	Title	Insulin und Glukagon im Blutplasma teilhepatektomierter Ratten Insulin and Glucagon in the Blood Plasma of Partial Hepatectomized Rats
	Abstract	U p to 4 weeks after partial hepatectomy the concentrations o f im m unoreactive insulin and glucagon in the blood plasma of rats were determined. Furtherm ore we m easured the activity of acid phosphatase in the serum, the concentration of cyclic AM P in liver cells, the activities of acid phosphatase in whole liver cells and in the cytosol of liver cells after partial hepatectomy. 2 h after partial hepatectom y there was a decline of the concentration o f insulin in the plasm a to about 13% of the initial value. 12 h after surgery a 5-fold increase of glucagon was found in the plasma. Shortly after this cyclic AMP reached its highest concentration. The activity of acid phosphatase in the whole liver cells and in the cytosol decreases slightly in the first 24 h after surgery whereas there is an increase o f the activity of acid phosphatase in the serum.
	Reference	Z. Naturforsch. 35c, 65—7 (1980); eingegangen am 2. M ärz/2. August 1979
	Published	1980
	Keywords	Rat, Partial Hepatectomy, Blood Plasma, Glucagon, Insulin
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	TEI-XML for	default:Reihe_C/35/ZNC-1980-35c-0065.pdf
	Identifier	ZNC-1980-35c-0065
	Volume	35

2	Author	G. Csaba, P. Ková, Ágnes Inczefi, -G Onda	Requires cookie*
	Title	Insulin B ind ing S ite s Induced in the Tetrahymena by R at Liver R ecep tor A ntibody
	Abstract	Tetrahvmena cells treated with purified rabbit anti bodies to rat hepatocellular membrane exhibited a consider able increase in binding capacity on reexposure to the antibody 24 h later. Insulin binding was similarly enhanced by preexposure to the antibody, and vice versa, preex posure to insulin enhanced the later binding o f rat liver receptor antibodies. This suggests that (1) the Tetrahymena and the rat possess similar insulin receptors, and (2) the receptor antibody is also able to induce imprinting for itself as well as for insulin. Concanavalin-A, noted for binding overlap with insulin, failed to induce imprinting either for insulin or for antibodies to receptors, whereas the latter did induce imprinting for Concanavalin-A.
	Reference	Z. Naturforsch. 39c, 183 (1984); received July 4/A ugust 22 1983
	Published	1984
	Keywords	Tetrahymena, Receptor-antibody, Insulin, Binding Sites
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	TEI-XML for	default:Reihe_C/39/ZNC-1984-39c-0183_n.pdf
	Identifier	ZNC-1984-39c-0183_n
	Volume	39

3	Author	JiřinaK. Opoldová	Requires cookie*
	Title	Radiation Aggregates of Insulin
	Abstract	During the irradiation of aqueous solution of insulin (pH 1.8) the decrease o f original insulin molecules and the formation of radiation aggregates o f insulin was studied in dependence on the concentration of irradiation solution, on the doses and conditions o f irradiation (oxygenated and oxygen-free atmosphere, the presence of ?-butanol, addition o f [14C] amino acids). From the results obtained and results published earlier it may be assumed that in irradiated solution on insulin new covalent bonds between insulin molecules are formed at tyrosyl, phenylalanyl and cystyl radi cals; these radicals are formed by the action of both direct and indirect effect (at present pH 1.8 mainly of H atoms).
	Reference	Z. Naturforsch. 34c, 1139—1143 (1979); received January 22/M ay 4 1979
	Published	1979
	Keywords	G am m a-Irradiation, Insulin, Aqueous Solution, R adiation Aggregates
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	TEI-XML for	default:Reihe_C/34/ZNC-1979-34c-1139.pdf
	Identifier	ZNC-1979-34c-1139
	Volume	34

4	Author	M. Fouad, Mohamed Abd-El-Fattah, Reiner Scherer, Gerhard Ruhenstroth-Bauer	Requires cookie*
	Title	Effect of Glucocorticoids, Insulin and a Growth Promoting Tripeptide on the Biosynthesis of Plasma Proteins in Serum-Free Hepatocyte Cultures "Fouad
	Abstract	The effect o f cortisol, dexamethasone, insulin and a liver cell growth prom oting tripeptide on the secretion o f plasma proteins into the m edium o f rat hepatocytes in monolayer cultures was studied. Cortisol and dexamethasone resulted in ~ 2.5-fold increase in the fibrinogen synthesis with general supression of album in and a-lipoprotein synthesis. On the other hand, insulin inhibited the biosynthesis o f most plasma proteins except for the complem ent system and transferrin. Concentrations o f a-lipoprotein, a-1-mac roglobulin and haptoglobin were moderately elevated when the tripeptide Gly-His-Lys was applied in low concentra tion.
	Reference	Z. Naturforsch. 36c, 350—352 (1981); received September 19/December 15 1980
	Published	1981
	Keywords	Rat Hepatocytes, Cultures, Plasma Proteins, G lucocorti coids, Insulin
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	TEI-XML for	default:Reihe_C/36/ZNC-1981-36c-0350_n.pdf
	Identifier	ZNC-1981-36c-0350_n
	Volume	36