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'Inhibitors' in keywords Facet   section ZfN Section C:Volume 038  [X]
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1983 (4)
1Author    Jacek Wierzchowski, David ShugarRequires cookie*
 Title    Sensitive Fluorimetric Assay for Adenosine Deaminase with Formycin as Substrate; and Substrate and Inhibitor Properties of some Pyrazolopyrimidine and Related Analogues  
 Abstract    The nucleoside antibiotic formycin, 7-amino-3-(/?-D-ribofuranosyl)pyrazolo(4,3-d)pyrimidine, a structural analogue of adenosine, is deaminated about 10-fold faster by adenosine deaminase than adenosine itself, and is therefore a superior substrate for both routine assays and kinetic studies with the purified enzyme. The luminescence properties o f formycin have been profited from to develop a fluorimetric assay for adenosine deaminase which is considerably more sensi­ tive than the spectrophotometric procedure widely employed with adenosine as substrate. Exam­ ples are presented of its application to routine assays of adenosine deaminase levels in cellular extracts, as well as to kinetic studies with the purified enzyme, including the properties o f some pyrazolopyrimidine and purine substrates and inhibitors. 
  Reference    Z. Naturforsch. 38c, 67—7 (1983); received August 23 1982 
  Published    1983 
  Keywords    Formycin, Pyrazolopyrimidines, Adenosine Deaminase, Fluorimetric Assay, Inhibitors 
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 TEI-XML for    default:Reihe_C/38/ZNC-1983-38c-0067.pdf 
 Identifier    ZNC-1983-38c-0067 
 Volume    38 
2Author    Friedrich Jiittner, O. Ttm Ar BogenschützRequires cookie*
 Title    Geranyl Derivatives as Inhibitors o f the Carotenogenesis in Synechococcus PCC 6911 (Cyanobacteria)  
 Abstract    The ability of several geranyl derivatives to inhibit carotenoid synthesis in Synechococcus (Cyanobacteria) was measured using a cyanobacterial bioassay. The inhibitory activity o f differ­ ent molecules varied according to chain length and substituents. Pseudoionone, famesyl acetate, geranyl acetate, geranial and farnesol proved to be the most active derivatives tested. 6-Methylhept-5-en-2-one, farnesyl acetone, linalool and geranyl linalool exhibited no effect when employed in concentrations as high as 100 ppm. Besides phytofluene, C-carotene was accumu­ lated after application o f sublethal amounts o f active geranyl derivatives. Cell growth and chlorophyll a synthesis were only slightly affected under conditions were carotenoid synthesis was markedly inhibited. 
  Reference    Z. Naturforsch. 38c, 387 (1983); received January 26 1983 
  Published    1983 
  Keywords    Inhibitors, Carotenoid Synthesis, Pseudoionone, Famesol, Famesyl Acetate 
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 TEI-XML for    default:Reihe_C/38/ZNC-1983-38c-0387.pdf 
 Identifier    ZNC-1983-38c-0387 
 Volume    38 
3Author    W. S. Cohen, J. R. BartonRequires cookie*
 Title    The Use of 0 2-Evolving Subchloroplast Particles to Study Acceptor and Inhibitor Sites on the Reducing Side of Photosystem II  
 Abstract    Photosystem II particles that retain the ability to evolve 0 2 have been used to exam ine acceptor and inhibitor sites in the photosynthetic electron transfer chain between Q and plasto-quinone. Employing the water to dichlorobenzoquinone reaction to assay photosystem II activity, we have demonstrated that electron transport in thylakoids and particles is equally sensitive to inhibition by D C M U , dinoseb, metribuzin, H Q N O and DBMIB. Based on differential sensitivity to inhibition by D C M U vs. H Q N O or DBMIB, we suggest that when synthetic quinones, e.g. 2,6-dichlorobenzoquinone operate as Hill reagents in particles they are reduced primarily by the plastoquinone pool. W hen synthetic quinones, e.g. 5,6-m ethylenedioxy-2,3-dim ethyl benzoquinone act as autoxidizable acceptors they accept electron from the Q /B com plex at a point that is located between the D C M U and H Q N O (DBM IB) inhibition sites. 
  Reference    Z. Naturforsch. 38c, 793—798 (1983); received April 26 1983 
  Published    1983 
  Keywords    Thylakoids, Photosystem II Particles, Q uinones, Inhibitors, Electron Transfer 
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 TEI-XML for    default:Reihe_C/38/ZNC-1983-38c-0793.pdf 
 Identifier    ZNC-1983-38c-0793 
 Volume    38 
4Author    Ernst PriesnerRequires cookie*
 Title    Receptors for D i-U nsaturated Pherom one Analogues in the M ale Summerfruit Tortrix M oth  
  Reference    Z. Naturforsch. 38c, 874—8 (1983); received June 30 1983 
  Published    1983 
  Keywords    Sex Pherom ones, Inhibitors, T etradecadienyl A cetates, O lfactory Receptors, Adoxophyes, T ortricidae 
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 TEI-XML for    default:Reihe_C/38/ZNC-1983-38c-0874_n.pdf 
 Identifier    ZNC-1983-38c-0874_n 
 Volume    38