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'Indole Alkaloids' in keywords Facet   Publication Year 1981  [X]
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1981[X]
1Author    Werner Kohl, Barbara Witte, Gerhard HöfleRequires cookie*
 Title    Alkaloide aus Catharanthus roseus-Zellkulturen, II [1] Alkaloids from Catharanthus roseus Tissue Cultures, II [1]  
 Abstract    From the extract of Catharanthus roseus tissue cultures 16 different indole alkaloids have been isolated belonging to heteroyohimbane, aspidosperma and iboga types. The structures were deduced by UV, NMR and mass spectrometry. Ajmalicine (1) and catharanthine (16) were found to be the major constituents, tetra-hydroalstonine (2), akuammigine (3), 3-isoajmalicine (4), pleiocarpamine (6), akuammiline (6), tabersonine (7), 20-hydroxytabersonine (8), lochnericine (9), horhammericine (10), minovincinine (11), vindolinine (12), 20-epivindolinine (18), vindolinine -Nt -oxide (14) and 20-epivindolinine-Nb-oxide (16) could be determined as minor or trace alkaloids. 
  Reference    Z. Naturforsch. 36b, 1153—1162 (1981); eingegangen am 20. Mai 1981 
  Published    1981 
  Keywords    Indole Alkaloids, Catharanthus roseus, Cell Cultures 
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 TEI-XML for    default:Reihe_B/36/ZNB-1981-36b-1153.pdf 
 Identifier    ZNB-1981-36b-1153 
 Volume    36 
2Author    K.-H Knobloch, B. Hansen, J. Berlin, ForschungM B H, A. Bteilung, Pflanzliche Zellkulturen, M. Ascheroder WegRequires cookie*
 Title    Medium-Induced Formation of Indole Alkaloids and Concomitant Changes of Interrelated Enzyme Activities in Cell Suspension Cultures of Catharanthus roseus  
 Abstract    Recently m edium conditions have been developed which stim ulate the form ation of the indole alkaloid ajm alicine in cell suspension cultures o f Catharanthus roseus [6]. W hen cells were subjected to these conditions the alkaloid accum ulation was preceded by a 12-fold increase o f the specific activity o f tryptophan decarboxylase. The enzyme activity showed a maxim um two days after the cell transfer into the induction medium and subsequently declined. In contrast the activity of strictosidine synthase, the enzyme condensing tryptam ine and secologanin, was present over the entire measuring period at a constant level. The intracellular content of tryp­ tamine and ajmalicine increased during a period of 6 days after cell transfer and reached a plateau after that time. A possible regulatory function o f tryptophan decarboxylase in indole alkaloid biosynthesis is discussed. 
  Reference    Z. Naturforsch. 36c, 40—4 (1981); received N ovem ber 3 1980 
  Published    1981 
  Keywords    Catharanthus roseus, Indole Alkaloids, Tryptophan Decarboxylase, Strictosidine Synthase, Media Effects 
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 TEI-XML for    default:Reihe_C/36/ZNC-1981-36c-0040.pdf 
 Identifier    ZNC-1981-36c-0040 
 Volume    36