| 1 | Author
| M. Aurice, B. Erger, JeanC. Adet | Requires cookie* | | Title
| Isolation and Characterization of the Radiation-Induced Degradation Products of 2 -Deoxyguanosine in Oxygen-Free Aqueous Solutions  | | | Abstract
| The bulk o f the radiation-induced degradation products o f 2'-deoxyguanosine in oxygen-free aqueous solution have been separated by high performance liquid chrom atography and charac terized by various spectroscopic techniques including fast atom bom bardm ent mass spectrom etry, 'H NM R and circular dichroism. The two main decom position products result from the opening o f the imidazole ring and further rearrangement o f the sugar m oiety. In addition, the formation o f six other nucleosides was shown to involve sugar radicals with subsequent epim erization, re arrangement or cyclization reactions. | | |
Reference
| Z. Naturforsch. 40b, 1519—1531 (1985); received June 18 1985 | | |
Published
| 1985 | | |
Keywords
| 2'-D eoxyguanosine, Gamma Irradiation, Hydroxyl Radicals, 'H N M R Spectra, M odified N ucleosides | | |
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| default:Reihe_B/40/ZNB-1985-40b-1519.pdf | | | Identifier
| ZNB-1985-40b-1519 | | | Volume
| 40 | |
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