| | 1 | Author
| E. Dith, E. Bert, W. In, M. Olfgang, K. Uecke, R. Laus, C. Am Steiner, Hristian Vogel | Requires cookie* | | | Title
| Inhibition of Ergosterol Biosynthesis by Etaconazole in Ustilago maydis  | | | | Abstract
| The triazole fungicide etaconazole (C G A 6 4 251) interferes with the ergosterol biosynthesis in Ustilago m aydis by inhibiting the C-14 dem ethylation o f the sterol nucleus. During the late log growth phase o f U. m aydis a novel endogenous sterol m etabolite (14x-m ethyl-ergosta-8,24(28)-dien-3/?,6a-diol) was discovered and analyzed, which accumulates under the influence o f the fungicide. The structure o f this m etabolite points to a hydroxylation-dehydration m echanism for the introduction o f the double bond at C-5 during the ergosterol biosynthesis. In troduction | | | |
Reference
| Z. Naturforsch. 38c, 28 (1983); received July 22 1982 | | | |
Published
| 1983 | | | |
Keywords
| Fungal Lipids, Ergosterol, Inhibition, Etaconazole, Fungicide | | | |
Similar Items
| Find | | | DEBUG INFO
| | | | | TEI-XML for
| default:Reihe_C/38/ZNC-1983-38c-0028.pdf | | | | Identifier
| ZNC-1983-38c-0028 | | | | Volume
| 38 | |
|
