| 1 | Author
| B. Ert+, W. E. Ck, H. Ard T+, K. Jäkel, P. Moser, D. Sozzi+, C. Vogel | Requires cookie* | | Title
| Quantitative Structure Activity Relationships of Fungicidally Active Triazoles: Analogs and Stereoisomers of Propiconazole and Etaconazole  | | | Abstract
| The preparation of the four stereoisomers of propiconazole (TILT®) is described. Their inhibi tion of the 14a-C-demethylation of the sterol nucleus is examined and compared with the inhibi tion by the four stereoisomers of etaconazole (SONAX®). The quantitative structure-activity relationships (Q SAR) of substituted l,3-dioxolane-2-yl-methyltriazoles and l,3-dioxane-2-yl-methyltriazoles on in vivo fungicidal activity are investigated. | | |
Reference
| Z. Naturforsch. 44c, 85 (1989); received September 8. 1988 | | |
Published
| 1989 | | |
Keywords
| Propiconazole, Etaconazole, Triazoles, Fungicides, OSAR | | |
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| default:Reihe_C/44/ZNC-1989-44c-0085.pdf | | | Identifier
| ZNC-1989-44c-0085 | | | Volume
| 44 | |
2 | Author
| E. Dith, E. Bert, W. In, M. Olfgang, K. Uecke, R. Laus, C. Am Steiner, Hristian Vogel | Requires cookie* | | Title
| Inhibition of Ergosterol Biosynthesis by Etaconazole in Ustilago maydis  | | | Abstract
| The triazole fungicide etaconazole (C G A 6 4 251) interferes with the ergosterol biosynthesis in Ustilago m aydis by inhibiting the C-14 dem ethylation o f the sterol nucleus. During the late log growth phase o f U. m aydis a novel endogenous sterol m etabolite (14x-m ethyl-ergosta-8,24(28)-dien-3/?,6a-diol) was discovered and analyzed, which accumulates under the influence o f the fungicide. The structure o f this m etabolite points to a hydroxylation-dehydration m echanism for the introduction o f the double bond at C-5 during the ergosterol biosynthesis. In troduction | | |
Reference
| Z. Naturforsch. 38c, 28 (1983); received July 22 1982 | | |
Published
| 1983 | | |
Keywords
| Fungal Lipids, Ergosterol, Inhibition, Etaconazole, Fungicide | | |
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| default:Reihe_C/38/ZNC-1983-38c-0028.pdf | | | Identifier
| ZNC-1983-38c-0028 | | | Volume
| 38 | |
3 | Author
| MalcolmS. Buchanan3, Wolfgang Steglich3, Timm Ankeb | Requires cookie* | | Title
| Strobilurin N and Two Metabolites Related to Chorismic Acid from the Fruit Bodies of Mycena crocata (Agaricales)  | | | Abstract
| Strobilurin N (1), a new member of the strobilurin family of antibiotics, has been isolated from the toadstool Mycena crocata, together with dehydrochorismic acid lactone (5) and 3-[l-carboxyvinyl)oxy]benzoic acid (6), which are closely related to chorismic acid (10). Their structures were determined mainly by 'H and 13C NMR spectroscopy. Interestingly, strobi lurin N is the first strobilurin without antifungal activity | | |
Reference
| Z. Naturforsch. 54c, 463 (1999); received March 18/April 12 1999 | | |
Published
| 1999 | | |
Keywords
| Mycena crocata, Toadstool, Strobilurins, Chorismic Acid Derivatives, Fungicide | | |
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| default:Reihe_C/54/ZNC-1999-54c-0463.pdf | | | Identifier
| ZNC-1999-54c-0463 | | | Volume
| 54 | |
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