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1979 (1)
1Author    FouadM. Fouad, D. W. Aldron-EdwardRequires cookie*
 Title    In vitro Action of Gastric Mucosal Lysosomal Enzymes on Intracellular Gastric Glycoproteins  
 Abstract    The results show that incubation of gastric mucosal cells from rat at pH ~4.5 or in the presence of aspirin is associated with a specific increase in the activity of some acid-hydrolases. Intracellular glycoproteins, isolated by non-degradative techniques from rat or dog fundic mucosal cells, were found to be potential bio-substrates for these acid-hydrolyses. This may suggest that cleavage of the carbohydrate moieties of the intracellular and mucosal cell wall glycoproteins is a fundamental step in the development of gastric ulceration. A model for gastric lesions is proposed and discussed in the light of the results obtained. 
  Reference    Z. Naturforsch. 34c, 90 (1979); received September 29/November 3 1978 
  Published    1979 
  Keywords    Gastric Ulceration, Fundic Glycoproteins, Aspirin, Lysosomal Enzymes 
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 TEI-XML for    default:Reihe_C/34/ZNC-1979-34c-0090.pdf 
 Identifier    ZNC-1979-34c-0090 
 Volume    34