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1992 (1)
1Author    W. Krol, J. Shani1, Z. Czuba, S. SchellerRequires cookie*
 Title    Modulating Luminol-Dependent Chemiluminescence of Neutrophils by Flavones  
 Abstract    The effect o f 14 flavones on luminol-dependent chemiluminescence o f neutrophils was stud­ ied in vitro. Chemiluminescence was used in this study as an indicator for the production o f a reactive oxygen species by neutrophils, stimulated by phorbol myristate acetate. While fla-vone-8-acetic acid, and most o f the com pounds tested, inhibited chemiluminescence, flavone and its 5-hydroxy-7-methoxy derivatives enhanced it by up to 150%. The m ost active inhibi­ tors o f photon emission were the glycosides. These results indicate that lipophilicity and some structural determinants modulate the chemiluminescent capacity o f neutrophils. 
  Reference    Z. Naturforsch. 47c, 889—8 (1992); received September 11 1992 
  Published    1992 
  Keywords    Chemiluminescence, Luminol, Radical Scavenging, Flavones, Neutrophils 
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 TEI-XML for    default:Reihe_C/47/ZNC-1992-47c-0889.pdf 
 Identifier    ZNC-1992-47c-0889 
 Volume    47