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1995 (1)
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1Author    W. Krol, J. Shani1, Z. Czuba, S. SchellerRequires cookie*
 Title    Modulating Luminol-Dependent Chemiluminescence of Neutrophils by Flavones  
 Abstract    The effect o f 14 flavones on luminol-dependent chemiluminescence o f neutrophils was stud­ ied in vitro. Chemiluminescence was used in this study as an indicator for the production o f a reactive oxygen species by neutrophils, stimulated by phorbol myristate acetate. While fla-vone-8-acetic acid, and most o f the com pounds tested, inhibited chemiluminescence, flavone and its 5-hydroxy-7-methoxy derivatives enhanced it by up to 150%. The m ost active inhibi­ tors o f photon emission were the glycosides. These results indicate that lipophilicity and some structural determinants modulate the chemiluminescent capacity o f neutrophils. 
  Reference    Z. Naturforsch. 47c, 889—8 (1992); received September 11 1992 
  Published    1992 
  Keywords    Chemiluminescence, Luminol, Radical Scavenging, Flavones, Neutrophils 
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 TEI-XML for    default:Reihe_C/47/ZNC-1992-47c-0889.pdf 
 Identifier    ZNC-1992-47c-0889 
 Volume    47 
2Author    KarinM. Valant-Vetscheraa, Eckhard WollenweberbRequires cookie*
 Title    Flavonoid Aglycones from the Leaf Surfaces of Some Artemisia spp. (Com positae-Anthem ideae)  
 Abstract    Several species of the large genus Artemisia have been analysed for the flavonoid aglycone composition of their leaf exudates. These species belong to different taxonomic groups within Artemisia. Flavone and flavonol aglycones were found as the major flavonoid constituents of the leaf exudates. Many of these compounds were 6-methoxylated, with additional substitu­ tions at the 7-, 3'-and 4'-position of the molecule. In addition, 7,4'-substituted apigenin and luteolin derivatives and rarely also coumarin derivatives were encountered in some species. The observed substitution trends are in accordance with literature data. Taxonomic and eco­ logical aspects are briefly discussed. 
  Reference    Z. Naturforsch. 50c, 353—357 (1995); received January 23/February 27 1995 
  Published    1995 
  Keywords    Artemisia, Compositae-Anthemideae, Leaf Exudates, Flavones, Coumarins 
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 TEI-XML for    default:Reihe_C/50/ZNC-1995-50c-0353.pdf 
 Identifier    ZNC-1995-50c-0353 
 Volume    50 
3Author    Satoshi Tahara, JohnL. Ingham, Junya MizutaniRequires cookie*
 Title    Substrate Specificity in the Fungal Metabolism of Prenylated Flavonoids  
 Abstract    The prenylated flavonoids, topazolin [5,7,4'-trihydroxy-3-methoxy-6-(3,3-dimethylaIlyl)-flavone], piscerythrone [5,7,2',4'-tetrahydroxy-5'-methoxy-3'-(3,3-dimethylallyl)isoflavone] and piscidone [5,7,4',5'-tetrahydroxy-2'-methoxy-6'-(3,3-dimethylallyl)isoflavone] were meta­ bolized by Aspergillus flavus and Botrytis cinerea to give a variety of products. Topazolin and piscerythrone were converted by both fungi to com pounds similar to those previously ob­ tained from luteone (6-prenyl) and licoisoflavone A (3'-prenyl) respectively. The 6'-prenylated isoflavone piscidone was metabolized only by B. cinerea to give the corresponding dihydro-pyrano-isoflavone as a m ajor product. N either fungus was found to metabolize the 8-prenylated pyranoflavanonol lupinifolinol. 
  Reference    Z. Naturforsch. 46c, 341—348 (1991); received January 181991 
  Published    1991 
  Keywords    Prenylated Isoflavones, Flavone, Aspergillus fla m s, Botrytis cinerea, Fungal Metabolism, Piscidone, Piscerythrone, Topazolin 
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 TEI-XML for    default:Reihe_C/46/ZNC-1991-46c-0341.pdf 
 Identifier    ZNC-1991-46c-0341 
 Volume    46