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'Deuterium' in keywords
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1988 (1)
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1977 (1)
1Author    L. Sportelli, A. Desideri, A. CamRequires cookie*
 Title    Isotopic Effect on the Kinetic of Thermal Denaturation of Ceruloplasmin  
 Abstract    The kinetics of thermal denaturation of ceruloplasmin in water and in water with different percentage of D20 in the temperature range 25 — 85 °C, following the optical density change of the 610 nm charge transfer band of the protein has been investigated. A temperature Tt — 65 °C above which an irreversible denaturation process of the protein active site takes place has been found. The kinetics of the denaturation process of the protein are fitted by two first order reactions, which have been assigned to a different thermal denaturation behaviour of the two Cu2+ type I sites existing in the protein. Addition of D 20 to the protein solution affects the two kinetics in a different way, i.e. the rate of one of them is increased whilst that of the other is decreased. The different effect of D20 on the kinetics of disruption of the two copper sites is discussed in terms of different location and degree of hydrophobicity of the two Cu2+ type I sites. 
  Reference    Z. Naturforsch. 40c, 551 (1985); received December 4 1984/March 18 1985 
  Published    1985 
  Keywords    Ceruloplasmin, Deuterium, Optical Absorption, Thermal Denaturation 
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 TEI-XML for    default:Reihe_C/40/ZNC-1985-40c-0551.pdf 
 Identifier    ZNC-1985-40c-0551 
 Volume    40 
2Author    M. Wenzel, Y. Wu, E. Liss, E. W. NeuseRequires cookie*
 Title    Stabilität des Ferricinium-Kations und seine cytostatische Wirkung Stability of Ferricinium and its Cytostatic Effect  
 Abstract    The relative stabilities of different ferricinium cations were studied in buffer or serum-containing solution and in vivo and compared with their cytostatic effects in cultures of Yoshida ascites tumor cells. Although the ferricinium cation itself was the most un-stable cation compared with the dimethyl-ferricinium ca-tion and the deuterated ferricinium derivatives it showed the highest cytostatic effect. 
  Reference    Z. Naturforsch. 43c, 963—966 (1988); received April 5 1988 
  Published    1988 
  Keywords    Ferricinium, Dimethyl-ferricinium, Deuterium, Tumor Cells, Cytostatic Effect 
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 TEI-XML for    default:Reihe_C/43/ZNC-1988-43c-0963_n.pdf 
 Identifier    ZNC-1988-43c-0963_n 
 Volume    43 
3Author    N.Requires cookie*
 Title    Exchange o f a H A tom s for D euterium and T ritium in Cyclic N-Nitrosamines  
  Reference    (Z. Naturforsch. 32b, 240 [1977]; received October 20 1976) 
  Published    1977 
  Keywords    Exchange, Deuterium, Tritium, Di-N-nitrosohomo-piperazine, Di-N-nitroso-2, 6-dimethylpiperazine 
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 TEI-XML for    default:Reihe_B/32/ZNB-1977-32b-0240_n.pdf 
 Identifier    ZNB-1977-32b-0240_n 
 Volume    32