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'Cytotoxic' in keywords Facet   Publication Year 1997  [X]
Facet   section ZfN Section C:Volume 052  [X]
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1Author    Eckhard Thines3, HeidrunA. Nke3-, Wolfgang Steglichb, Olov SternercRequires cookie*
 Title    New Botrydial Sesquiterpenoids from Hymenoscyphus epiphyllus  
 Abstract    Four new botrydial derivatives, hymendial (1), 7a-hydroxydihydrobotrydial (2), 701-hy­ droxy-10-0-methyldihydrobotrydial (4), and 7a-acetoxy-15a-methoxy-10-0-methyl-dihydro-botrydial (5) were isolated together with dihydrobotrydial (3) from the culture fluid of the ascomycete Hymenoscyphus epiphyllus. In addition, cytochalasin H (6a), 18-deoxycytocha-lasin H (6b) and (+)-mellein (7) were produced by this fungus. Hymendial (1), possessing an a, ß-unsaturated dialdehyde functionality, exhibits antimicrobial and cytotoxic activities and is mutagenic in the Ames Salmonella assay. 
  Reference    Z. Naturforsch. 52c, 413—420 (1997); received April 22/June 6 1997 
  Published    1997 
  Keywords    Hymenoscyphus epiphyllus, Botrydial Derivatives, Antimicrobial, Cytotoxic, Mutagenic 
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 TEI-XML for    default:Reihe_C/52/ZNC-1997-52c-0413.pdf 
 Identifier    ZNC-1997-52c-0413 
 Volume    52