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'Cytotoxic' in keywords Facet   Publication Year 1982  [X]
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1Author    TimM. Anke, Bruno-MaxG. Iannetti, Wolfgang SteglichRequires cookie*
 Title    Antibiotika aus Basidiomyceten, XV [1]. l-Hydroxy-2-nonin-4  
 Abstract    on, ein antifungischer und cytotoxischer Metabolit aus Ischnoderma benzoinum (Wahl.) Karst. Antibiotics from Basidiomycetes. XV [1]. l-Hydroxy-2-nonyn-4-one, an Antifungal and Cytotoxic M etabolite from Ischnoderma benzoinum (W ahl.) Karst. A new antibiotic, 1-hydroxy-2-nonyn-4-one (1), has been isolated from submerged cultures of several strains of Ischnoderma benzoinum. The compound exhibits high inhibitory activity against yeasts and filamentous fungi at concentrations o f 1 -5 ng/ml. D N A , RNA, and protein syntheses in cells of the ascitic form o f Ehrlich carcinoma are strongly inhibited by the same concentrations. 
  Reference    Z. Naturforsch. 37c, 1—4 (1982); received October 31 1981 
  Published    1982 
  Keywords    Acetylenic Metabolite, Antifungal, Cytotoxic 
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 TEI-XML for    default:Reihe_C/37/ZNC-1982-37c-0001.pdf 
 Identifier    ZNC-1982-37c-0001 
 Volume    37