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'Cytotoxic Activity' in keywords Facet   section ZfN Section B  [X]
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1999 (1)
1Author    Ümmühan Dodofp, Nurcan Özdemirb, Milka Karacanb, Ch, SpiroM. Georgievac, MiglenaE. Konstantinov0, Stefanova6Requires cookie*
 Title    Nicolay I  
 Abstract    Three novel Schiff bases: salicylaldehyde methanesulfonylhydrazone (1), 2-hydroxyaceto-phenone methanesulfonylhydrazone (2) and 2-hydroxy-1-naphthaldehyde methanesulfonylhy­ drazone (3) have been synthesized. Compounds 1-3, as well as acetone methanesulfonylhydra­ zone (4) have been characterized by TLC, 'H NMR and IR spectra. The spectroscopic results for 1-3 have revealed the presence of an intramolecular hydrogen bond between the hydroxyl group and the imine N atom. The conformational isomerism of 1-4 with respect to the rota­ tions around the SN and NN bonds have been studied by the method of molecular mechanics. Compounds 1-4 and methanesulfonylhydrazine exhibit antibacterial and cytotoxic effects. 
  Reference    Z. Naturforsch. 54b, 1553—1562 (1999); received July 31 1999 
  Published    1999 
  Keywords    Schiff Bases, Methanesulfonylhydrazine, 'H NMR Data, M olecular Mechanics, Cytotoxic Activity 
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 TEI-XML for    default:Reihe_B/54/ZNB-1999-54b-1553.pdf 
 Identifier    ZNB-1999-54b-1553 
 Volume    54