| 1 | Author
| Ulrich Schraermeyer | Requires cookie* | | Title
| Effects of Chloroquine on the Photosensory Membrane Turnover and the Ultrastructure of Lysosome-Related Bodies of the Crayfish Photoreceptor  | | | Abstract
| The effect o f chloroquine in combination with bright light on the ultrastructure o f crayfish (Orconectes limosus R.) photoreceptors was investigated in vivo. Chloroquine had several ef fects upon the crayfish retina. Multivesicular bodies (M VB) that are involved in lysosom al degradation o f photosensory membrane were altered in ultrastructure. M VB frequently con tained smaller M VB in a state o f more advanced membrane degradation. A dditionally screen ing pigment-like granules appeared in MVB. MVB accumulated in and filled the retinular cell cytoplasm just proximal or distal to the basement membrane which indicated inhibition o f photosensory membrane degradation. Under chloroquine treatment rhabdom degradation appeared to be inhibited, as rhabdom diameter was less reduced under these conditions. A lso chloroquine caused accumulation o f screening pigment granules in glial cells within the lamina ganglionaris. | | |
Reference
| Z. Naturforsch. 47c, 420 (1992); received January 17 1992 | | |
Published
| 1992 | | |
Keywords
| Electron M icroscopy, Chloroquine, Crayfish, Photoreceptor, Screening Pigment Granules | | |
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| default:Reihe_C/47/ZNC-1992-47c-0420.pdf | | | Identifier
| ZNC-1992-47c-0420 | | | Volume
| 47 | |
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