| 1 | Author | H.Peter Matthiessen, H.Rainer Maurer | Requires cookie* |
| Title | Low Molecular Mass Inhibitors from Calf Thymus Selective for T-Lymphocyte Proliferation  | ||
| Abstract | Endogenous factors preferentially inhibiting T-lympho-cyte proliferation were prepared from the acetone precipi tate of a 60% ethanol extract from calf thymus and their biochemical properties examined. By ultrafiltration the strongest lymphocyte-selective inhibition was found in the molecular mass range between 1 and 5 kDa. Fast protein liquid chromatography (FPLC) of this fraction on an anion exchange column eluted the lymphocyte inhibitors at 205—265 mM ammonium acetate. Staining procedures following IEF and TLC suggested, that the inhibitors may not be glycoconjugates or amines but small weakly acidic peptides (< 3 kDa). | ||
| Reference | Z. Naturforsch. 41c, 1131 (1986); received November 11 1985/July 18 1986 | ||
| Published | 1986 | ||
| Keywords | Lymphocyte Proliferation Inhibitors, Calf Thymus, Peptides, Chalone, Colony Formation | ||
| Similar Items | Find | ||
